**9. Points to remember**

*Prediction of Maternal and Fetal Syndrome of Preeclampsia*

treatment must be the same as in the general population.

high negative predictive value.

**moderate. Recommendation, strong.**

**Recommendation, strong.**

**Recommendation, strong.**

disease severity is.

from the age of 2 years.

the fetus from sequelae.

offspring [34, 35].

2.Prophylactic aspirin before the 16th week of gestation in patients at greatest

3.In the second trimester, a uterine Doppler combined with other variables has a

Since there is no defined pattern in adolescent preeclampsia, its diagnosis and

Care of pregnant adolescents must be provided in *ex profeso* clinics with complete, integral, and multidisciplinary programs to decrease maternal and perinatal risks, including pregnancy-induced hypertension. **Level of evidence, moderate.** 

Although there is no evidence on the beneficial effect of interventions used to curb weight gain during pregnancy, offering a medical evaluation and nutritional counseling is a good practice to recommend. **Level of evidence, low.** 

Every adolescent clinic must establish the incidence of preeclampsia and eclampsia in its patient population and determine which factors are associated to

According to the diagnostic situation of preeclampsia and eclampsia in each adolescent clinic, screening, preventive, early detection, and therapeutic programs must be designed. **Level of evidence, moderate. Recommendation, strong.**

Follow-up of the offspring of mothers with any pregnancy-associated hypertensive state [33] has shown that by age 7, their systolic blood pressure is increased although within normal parameters—SBP of 104 mm Hg (95%CI 101–106 vs. SBP 99 mm Hg, 95%CI 99–100, p = 0.001)—and this cardiometabolic injury is evident

This abnormality is only observed in full-term births and not in premature offspring; a posited explanation is that the stress caused by preterm delivery protects

Another consequence observed in the offspring of hypertensive mothers is the development of hypertension and cerebral vascular disease when these children reach adulthood. Also, their risk of developing hypertension increases if their body mass index is elevated, and this has been observed since the ages of 4–10, even if the mother had hypertension with no proteinuria; the presence of elevated liver enzymes or thrombocytopenia has also been associated with hypertension in young

In adolescents with preeclampsia, the disease is generally manifested in the latter part of gestation, close to full-term delivery, so good prenatal care fosters a timely diagnosis of hypertensive disease in earlier stages and improves maternal and fetal outcomes. In the case of the induction of delivery, outcomes will also be improved by decreasing the need for cesarean delivery even in the cases of severe preeclampsia: the neonatal outcome also improves since age is not an influencing factor but

their development. **Level of evidence, low. Recommendation, strong.**

**8. Long-term fetal complications in hypertensive mothers**

Therefore, the following recommendations have been established [32]: In pregnant adolescents, screening, diagnostic, and therapeutic interventions should be similar to those applied in the rest of the population. **Level of evidence,** 

risk, based on an abnormal uterine Doppler in the first trimester.

**134**


*Prediction of Maternal and Fetal Syndrome of Preeclampsia*
