**6. Conclusion**

On the basis of our *in silico* analyses, we can conclude that halocin production is considered as a general feature of some members of halophilic archaea, particularly members of *Natrialbales* and *Haloferacales* orders with the occurrence of Halocin C8-like production. This group can thrive in saline ecosystems in which several other microorganisms are not able to live. Thus, the dominance of certain species isolated in some saline ecosystems could be attributed to halocin production as a mechanism of competition between microrganisms. This chapter will open new research lines that will shed light on halocins as marker for haloarchaeal phylogentic delineation.
