Preface

Heterocyclic systems are important building blocks for new materials possessing interesting electronic, mechanical, or biological properties. For more than a century, many heterocycles have constituted the largest areas of research in organic chemistry. Heterocycles play an important role in biochemical processes because the side groups of the most typical and essential constituents of living cells, DNA and RNA, are based on aromatic heterocycles. The presence of heteroatoms results in significant changes in the cyclic molecular structure due to the availability of unshared pairs of electrons and the difference in electronegativity between heteroatoms and carbon.

Many synthetic methods have been developed for the preparation of heterocycles. The current book project covers the basics and advanced utility of heterocycles in biochemistry, industrial chemistry, environmental sciences, pharmacy, microbiology, biotechnology, and related disciplines. Also, it will fulfill the requirement for new approaches in experimental skills and solving problems obtained during functional group transformation. This book provides a broad range of solutions to the problems of graded difficulties from organic reactions, rearrangements, and reagents along with their isolation and synthetic applications. The main goal of this book is to build on the foundation of synthesis and characterization. Special emphasis has been placed on the synthesis and mechanism of the reactions of different classes of heterocycles. Furthermore, it will bridge the gap between teaching, research, and practice. Finally, this book project provides a concise and comprehensive overview of the methods and biological importance of heterocyclic compounds synthesis.

**II**

**Section 2**

Derivatives

Thiazolo Pyrazoles *by Avula Srinivas*

New Millennium

*and Rajendra S. Dongre*

Azoles as Potent Antimicrobial Agents *by Rohit Singh and Swastika Ganguly*

*by Yamajala B.R.D. Rajesh*

Synthetic and Biological Activity Section **105**

**Chapter 8 107**

**Chapter 9 117**

**Chapter 10 133**

**Chapter 11 151**

**Chapter 12 171**

Synthesis and Anticancer Evaluation of Benzenesulfonamide

*by Dattatraya Navnath Pansare and Rohini Narayan Shelke*

Synthesis and Biological Evaluation of Novel Phosphonyl

Potent Antibacterial Profile of 5-Oxo-Imidazolines in the

*by Roshan D. Nasare, Mohammad Idrees, Satish S. Kola* 

Quinoline Heterocycles: Synthesis and Bioactivity

**B.P. Nandeshwarappa** Davangere University, India

**Sadashiv S.O.** Garden City University, India

**1**

Section 1

Synthetic Section
