Meet the editor

Takashiro Akitsu, PhD, is a professor in the Department of Chemistry, Faculty of Science at Tokyo University of Science. He completed his undergraduate school training (chemistry) at Osaka University, Japan, and his graduate school training (physical and inorganic chemistry, especially coordination, crystal and bioinorganic chemistry) also at Osaka University (PhD 2000). After Keio University and Stanford University, he moved to his

current affiliation in 2008. Dr. Akitsu has published up to 190 articles in peer-reviewed journals and has had posters presented at international level. He has been a peer reviewer of many journals and acted on the organizing committees of several international conferences. His main interests are absorption of light by chiral metal complexes and their hybrid functional materials.

**Preface III**

**Chapter 1 1**

**Chapter 2 9**

**Chapter 3 19**

**Chapter 4 55**

**Chapter 5 77**

**Chapter 6 99**

*by Aleksandra Ageeva, Ekaterina Khramtsova, Ilya Magin, Nikolay Polyakov,* 

Chirality and Circular Polarized Properties of Photochromic Polyaromatic

Introductory Chapter: Chirality from Molecular Electronic States

Chirality Properties of Modeling Water in Different Aqueous Systems *by Khakhalin Andrey Vladimirovich and Gradoboeva Olga Nikolaevna*

Peculiarities of Electron Transfer in Chiral Linked Systems

*by Tsuyoshi Sawada, Shingo Kubo and Kazuaki Nanamura*

*by Takashiro Akitsu*

Contents

The Nonlinear Analysis of Chiral Medium

Chirality in Porous Functional Materials

*by Shumaila Ashraf and Bo Wang*

*Miguel Miranda and Tatyana Leshina*

Molecules

*by Andrey Nikolaevich Volobuev*

## Contents


Preface

In chemistry, biology, and physics, "chirality" is an important concept in nature. Especially in chemistry, not only classical stereochemistry but also asymmetric organic synthesis, supramolecular chemistry, construction of bio-related molecules and molecular recognition became indispensable structural chemical keywords. However, in view of synthetic chemistry and its structural chemistry, chemistry dealing with chirality in relation to the more fundamental electronic state is still a minority. This book is particularly aimed at chiroptical spectroscopy, structural or

Indeed, as in many prefaces of numerous textbooks (mainly for chemistry) on this subject, one can easily understand that chirality (not only structural but also

"*Chirality is a phenomenon that is manifested throughout the natural world, ranging from fundamental particles through the realm of molecules and biological organisms to spiral galaxies. Thus, chirality is of interest to physicists, chemists, biologists, and astronomers. Chiroptical spectroscopy utilizes the differential response of chiral objects to circularly polarized electromagnetic radiation. Applications of chiroptical spectroscopy are widespread in chemistry, biochemistry, biology, and physics. It is indispensable for stereochemical elucidation of organic and inorganic molecules. Nearly all biomolecules and natural products are chiral, as are the majority of drugs. This has led to crucial applications of chiroptical spectroscopy ranging from the study of protein folding to* 

"*Chiroptical data were acquired as early as the mid nineteenth century, and are thus among the earliest types of physical constants measured. Despite this, and the inherent importance of chiroptical phenomena and chirality, measurement of optical activity is one of the most underutilized of all spectroscopic techniques. Among the factors that lead to this unfortunate trend were the large gaps in our understanding of the relationship between theory and applications, and the empirical nature of many rules used in data interpretation. Fortunately, recent years have brought rapid changes in this situation.*"

I express my heartfelt gratitude to Ms. Maja Bozicevic et al. for their concern,

Department of Chemistry, Faculty of Science, Tokyo University of Science,

efforts, and support in the task of publishing this volume.

*N. Berova, P. L. Polavarapu, K. Nakanishi, R. W. Woody* [1]

*N. Berova, K. Nakanishi, R. W. Woody* [2]

**Takashiro Akitsu**

Tokyo, Japan

physical features and theoretical computation about chirality.

electronic aspects) may be one of the important terms in science.

*characterization of small molecules, pharmaceuticals, and nucleic acids.*"
