**8. Central venous catheters**

The use of central venous catheters (CVCs) in the treatment of children with musculoskeletal infection has raised the concern that these catheters may be associated with risk including DVT development. Our review noted the concurrent presence of CVLs in several children with DVT, but the conclusions were generally that there was no clear relationship.5,6,9 Hollmig et al. found that CVCs were used in all eleven children with osteomyelitis and DVT in their series.9 However, there did not appear to be a relationship between the location or temporal onset of the DVT to the CVC in their experience.9
