*4.2.2 Tantalus gastric electrical stimulatory device*

The Tantalus Electrical Stimulatory Device (Metacure, Israel) is a pulse generator accommodated with three bipolar leads. The device is designed to create an early activation of physiological satiety by enhancing physiological signals of gastric distensions and contractions. The system is capable of delivering gastric contractility modulation (GCM) signals triggered by food. The device senses spontaneous electrical activity of the smooth muscles and then delivers signals to enhance them. With the use of a specialized algorithm of electro-mechanical parameters in the gut, the system can detect the onset of a meal. It is hypothesized that enhancing of spontaneous gastric contractions in a very early stage of the meal, before reaching full gastric distension, induced early satiety by stimulation of stretch receptors. These elicit an increased input to the CNS, thereby promoting a feeling of fullness.
