**11. References**


Pathophysiology and Clinical Aspects of 166 Venous Thromboembolism in Neonates, Renal Disease and Cancer Patients

We realize that there are many claims that never comes to the knowledge of the DPIA. The reasons for this are many: Ignorance of the law, resignation in the face of a serious disease complicated by the injury, the bother of the application procedure, fear of alienating the physician etc. We have tried several methods in order to achieve a more precise estimate of this problem (9, 10). Our best estimate is now that there are at least 4 – 5 patient injuries for

The risk of VTE increases with malignancy, infections, reoperations and surgery close to the large veins. The prophylaxis should be adjusted accordingly. It is about time that the medical profession starts to realize that posttraumatic or postoperative VTE is not an inevitable event. It may be prevented by a number of quite effective measures, but a change

[3] Bottaro FJ, Elizondo MC, Doti C, Bruetman JE, Perez Moreno PD, Bullorsky EO,Ceresetto

[5] Schulman S, Majeed A. A benefit-risk assessment of dabigatran in the prevention of venous thromboembolism in orthopaedic surgery. Drug Saf. 2011;34(6):449-63. [6] Bovio JA, Smith SM, Gums JG. Dabigatran etexilate: a novel oral thrombin inhibitor for

[7] Ruppert A, Steinle T, Lees M. Economic burden of venous thromboembolism:

[8] No authors listed. Evidence exists to guide thromboembolic prophylaxis in ambulatory

[9] Erichsen M, Rasmussen CW, Christoffersen JK. Pulmonary embolism with lethal

[10] Petersen HØ, Rasmussen AH, Andersen LI, Christoffersen JK. Mediastinitis following

patients with temporary lower limb immobilisation. Emerg Med J. 2011;28(8):718-

outcome and claims to the Danish Patient Insurance Association. Ugeskr læg 2008;

cardiac surgery. Patient insurance reports. Ugeskrift for læger 2008; 170(22): 1907-

thromboembolic disease. Ann Pharmacother. 2011;45(5):603-14.)

asystematic review. J Med Econ. 2011;14(1):65-74.

JM. Efficacy of extended thrombo-prophylaxis in major abdominalsurgery: what does the evidence show? A meta-analysis. Thromb Haemost. 2008;99(6):1104-11. [4] Rasmussen MS, Jorgensen LN, Wille-Jørgensen P, Nielsen JD, Horn A, Mohn AC,Sømod

L, Olsen B; FAME Investigators. Prolonged prophylaxis with dalteparin to prevent late thromboembolic complications in patients undergoing major abdominal surgery: a multicenter randomized open-label study. J Thromb Haemost.

[1] Brownwall E. Textbook of Cardiology p. 985. WB Saunders, Philadelphia 1988

[2] http://www.patientforsikringen.dk/en/Love-og-Regler.aspx.

each claim.

**11. References** 

20.

1908,

in attitude from the medical profession is required.

2006;4(11):2384-90.

170(22): 1909-1912

*Edited by Mohamed A. Abdelaal*

Venous Thromboembolism remains a major health challenge in many countries because of the morbidity and mortality it inflicts, mainly in hospitalized patients. This book, with contributions from distinguished experts in the field, depicts some hot aspects on aetilogics of VTE, the disease burden in neonates, renal disease and cancer patients as well as issues relevant to prophylaxis and the concept of VTE as patient injury content.

Photo by PhonlamaiPhoto / iStock

Pathophysiology and Clinical Aspects of Venous Thromboembolism in

Neonates, Renal Disease and Cancer Patients

Pathophysiology and

Clinical Aspects of Venous

Thromboembolism in

Neonates, Renal Disease and

Cancer Patients

*Edited by Mohamed A. Abdelaal*