**5. Pomalidomide and thrombosis**

Pomalidomide (CC4047) is a new IMiD with high *in vitro* potency. In a phase 1 trial evaluating CC-4047 alone in 24 patients with RRMM, 4 (17%) developed a TEE during the first year of therapy [73]. Thromboprophylaxis was given in the phase 2 studies of pomalidomide and low-dose dexamethasone [74-78].
