**3. Medicinal plants with demonstrated activity against** *Vibrio cholera*

 Cholera is an acute intestinal disease caused by a facultative anaerobic, Gramnegative, comma-shaped rod bacterium, known as *V. cholerae*. Cholera is a life threatening disease transmitted by the fecal-oral route. The organisms adhere to and colonize the small bowel within a short incubation period, where they secrete cholera enterotoxin leading to severe and watery diarrhea accompanied with vomiting, dehydration and eventually death if not treated promptly [37]. Various antibiotics have been effective for the treatment of cholera; however, the worldwide problem of microbial resistance to existing antimicrobial medicines has led to most antibiotic failure. Researchers are therefore shifting their focus to natural products, especially medicinal plant, with effective antimicrobial properties. Some medicinal plants with potent anti-cholera activity are reviewed below.
