**2.12** *Azadirachta indica*

*A. indica* A. Juss is commonly known as neem tree or Indian lilac and belongs to the mahogany family Meliaceae. It is an evergreen, fast-growing tree that can reach a height of 15–20 m with few of them growing up to 35–40 m, but in severe drought it may shed most of its leaves or nearly all leaves. It is typically grown in tropical and semi-tropical regions. Neem is effective against certain fungi that infect humans and hence used to treat skin diseases like eczema, psoriasis [34]. The 80% methanol leaf extract showed *in vitro* anti-plasmodial activity against chloroquine and pyrimethamine sensitive, 3D7 strain, and chloroquine resistant and pyrimethamine sensitive, Dd2 strain, with IC50 of 5.8 and 1.7 μg/mL, respectively [35].
