**3.1** *Terminalia chebula*

*T. chebula* Retz. (Combretaceae) commonly known as black or chebulic myrobalan is a medium to large deciduous tree growing up to 30 m tall, with a trunk of 1 m in diameter. It leaves are oval, alternate to subopposite in arrangement and is

a native to South Asia, from India and Nepal east to southwest China, Sri Lanka, Malaysia and Vietnam. Traditionally, it has been used for treatment of indigestion, diarrhea and diabetes [38]. The plant extract used to treat Cholera worked effectively against the strains of *V. cholera* the causative agent. The methanol fruit extract of *T. chebula* had strong bactericidal activity with MIC ranging from 0.125 to 1.5 mg/mL and MBC ranging from 0.25 to 2 mg/mL, against multi-drug resistance strains of *V. cholerae* (serotypes O1, O139, and non-O1, non-O139) [39].
