**2.11 Hemslecin A (12′)**

Three cucurbitane triterpenoids were isolated from *H. amabilis*, and the main compound was Hemslecin A (HA). This compound showed significant cytotoxic activity against HeLa cells with an IC50 value of 0.389 μM. Additionally, 7β-hydroxycucurbitacin F-25-O-acetate (**13′**) and 2β,3β,20(*S*),26,27-pentahydroxy-16α,23(*S*)-epoxycucurbita-5,24-dien-11-one (**14′**) (**Figure 2**) were isolated and showed less cytotoxic activity (IC50 values of 12.3 and 387 μM, respectively) than HA [29].
