**Conflict of interest**

Xavier Carbonell-Estrany has acted as expert advisor and speaker for AbbVie and has received honoraria for this. Bosco Paes has received research funding and compensation as advisor and lecturer from AbbVie Corporation. Barry Rodgers-Gray is an employee of Strategen; Strategen has received fees for work on various projects for AbbVie. The authors have no other conflict of interest to declare.
