Contents

### **Preface XIII**



**Part 2 Tropical Diseases Due to Protozoa and Helminths 137**  Chapter 10 **Malaria Chemoprophylaxis for the International Traveler, Current Options and Future Possibilities 139**  Ross Parker and Kevin Leary Chapter 11 **Effects of Irrigated Rice Fields and Seasonality on**  *Plasmodium* **Transmission in West Africa, Particularly in Central Côte d'Ivoire 155**  Benjamin G. Koudou, Marcel Tanner and Juerg Utzinger Chapter 12 **Toxoplasmosis: Advances and Vaccine Perspectives 169**  Oscar Bruna-Romero, Dulcilene Mayrink de Oliveira and Valter Ferreira de Andrade-Neto Chapter 13 **Screening of the Prevalence of Antibodies to the Tick**  *Hyalomma lusitanicum* **in a Province of Northern Spain 185**  Consuelo Giménez Pardo and Lourdes Lledó García Chapter 14 **Amoebiasis in the Tropics: Epidemiology and Pathogenesis 201**  A. Samie, A. ElBakri and Ra'ed AbuOdeh Chapter 15 **Retrospective Analysis of Leishmaniasis in Central Tunisia: An Update on Emerging Epidemiological Trends 227**  Akila Fathallah Mili, Fatma Saghrouni, Zeineb BenSaid, Yusr Saadi- BenAoun, Ikram Guizani and Moncef BenSaid Chapter 16 **Current Advances in Computational Strategies for Drug Discovery in Leishmaniasis 253**  Andrés F. Flórez, Stanley Watowich and Carlos Muskus Chapter 17 **Advances in Serological Diagnosis of Chagas' Disease by Using Recombinant Proteins 273**  Iván S. Marcipar and Claudia M. Lagier Chapter 18 **Echinococcosis/Hydatidosis 299**  Antoni Soriano Arandes and Frederic Gómez Bertomeu Chapter 19 **A Programme to Control Taeniosis-Cysticercolsis (***Taenia solium***) in Mexico 323**  Aline S. de Aluja, Julio Morales Soto and Edda Sciutto Chapter 20 **Antischistosomal Natural Compounds: Present Challenges for New Drug Screens 333**  Josué de Moraes Chapter 21 **Control of Schistosomiasis and Soil-Transmitted Helminthiasis in Sub-Saharan Africa: Challenges and Prospects 359**  Louis-Albert Tchuem Tchuenté

Contents VII

Chapter 22 **Hyperinfection Syndrome in Strongyloidiasis 377**  Cristiane Tefé-Silva, Eleuza R. Machado, Lúcia H. Faccioli and Simone G. Ramos

> **Benzimidazole Susceptibility of Human Filariids 397**  Adisak Bhumiratana, Apiradee Intarapuk, Danai Sangthong, Surachart Koyadun, Prapassorn Pechgit and Jinrapa Pothikasikorn

Chapter 23 **Molecular Diagnosis and Monitoring of** 

Chapter 24 **Lymphatic Filariasis Transmission and Control:** 

Asep K. Supriatna and N. Anggriani

**Non-Infectious Conditions 443** 

Chapter 26 **Sexually Transmitted Infections in the Tropics 457**  John C. Meade and Denise C. Cornelius

Chapter 27 **Re-Emergence of Malaria and Dengue in Europe 483**  Rubén Bueno Marí and Ricardo Jiménez Peydró

Chapter 28 **Neonatal Thermoneutrality in a Tropical Climate 513**

Chapter 29 **Associations Between Nutritional Indicators Using Geoadditive Latent Variable Models with** 

**Application to Child Malnutrition in Nigeria 545** 

Chapter 25 **Novel Molecular Diagnostic Platform for Tropical Infectious Diseases 445** Yasuyoshi Mori, Norihiro Tomita, Hidetoshi Kanda and Tsugunori Notomi

**Part 3 Other Tropical Infectious and** 

Hippolite O. Amadi

Khaled Khatab

**A Mathematical Modelling Approach 425** 

	- **Part 3 Other Tropical Infectious and Non-Infectious Conditions 443**

VI Contents

**Part 2 Tropical Diseases Due to Protozoa and Helminths 137**

Chapter 10 **Malaria Chemoprophylaxis for the International Traveler, Current Options and Future Possibilities 139** 

Benjamin G. Koudou, Marcel Tanner and Juerg Utzinger

*Hyalomma lusitanicum* **in a Province of Northern Spain 185**

Chapter 12 **Toxoplasmosis: Advances and Vaccine Perspectives 169**  Oscar Bruna-Romero, Dulcilene Mayrink de Oliveira and

Chapter 13 **Screening of the Prevalence of Antibodies to the Tick** 

**Epidemiology and Pathogenesis 201**  A. Samie, A. ElBakri and Ra'ed AbuOdeh

Chapter 16 **Current Advances in Computational Strategies for Drug Discovery in Leishmaniasis 253** 

Iván S. Marcipar and Claudia M. Lagier

Chapter 19 **A Programme to Control Taeniosis-Cysticercolsis (***Taenia solium***) in Mexico 323**

Chapter 21 **Control of Schistosomiasis and Soil-Transmitted Helminthiasis in Sub-Saharan Africa: Challenges and Prospects 359**  Louis-Albert Tchuem Tchuenté

Chapter 17 **Advances in Serological Diagnosis of** 

Chapter 20 **Antischistosomal Natural Compounds:** 

Josué de Moraes

Chapter 18 **Echinococcosis/Hydatidosis 299**

Consuelo Giménez Pardo and Lourdes Lledó García

Chapter 15 **Retrospective Analysis of Leishmaniasis in Central Tunisia:** 

**An Update on Emerging Epidemiological Trends 227** Akila Fathallah Mili, Fatma Saghrouni, Zeineb BenSaid, Yusr Saadi- BenAoun, Ikram Guizani and Moncef BenSaid

Andrés F. Flórez, Stanley Watowich and Carlos Muskus

Antoni Soriano Arandes and Frederic Gómez Bertomeu

Aline S. de Aluja, Julio Morales Soto and Edda Sciutto

**Present Challenges for New Drug Screens 333**

**Chagas' Disease by Using Recombinant Proteins 273**

Chapter 11 **Effects of Irrigated Rice Fields and Seasonality on**  *Plasmodium* **Transmission in West Africa, Particularly in Central Côte d'Ivoire 155** 

Ross Parker and Kevin Leary

Valter Ferreira de Andrade-Neto

Chapter 14 **Amoebiasis in the Tropics:** 


Preface

of the world (Franco-Paredes et al. 2007c).

allows it to reach a worldwide audience.

Tropical medicine research holds a special place as an important activity that as a consequence of multiple factors, such as globalization and migration has extended and reaffirms its importance not only in tropical developing countries but also in nonendemic areas in the developed world. The update on different aspects related to the practice of tropical medicine and their multiple components needs to be frequently visited. Three of the most important infectious terminal diseases in the world that belong or significantly affect tropical areas are AIDS, Tuberculosis and Malaria. These pathologies, together with other important ones, represent relevant public health problems, particularly in Africa, Asia and Latin America (Franco-Paredes et al. 2007a, Franco-Paredes et al. 2007b, Rodríguez Morales AJ et al. 2006, Rodríguez Morales AJ et al. 2008), secondarily affecting, due to travel, Europe, North America and other areas

Diseases and conditions as object of the study of tropical medicine are diverse in organ compromise as well as in etiology, including infectious and non-infectious agents. With these concepts in mind, this book includes different topics of tropical medicine of current international interest, trying to update the most significant research in many of them as well as offer a multinational perspective on different relevant conditions. This book has been organized in three major sections: I. Tropical Diseases due to Bacteria and Viruses; II. Tropical Diseases due to Protozoa and Helminths; and III. Other Tropical Infectious and Non-Infectious Conditions. Section I includes topics covering bacterial diseases such as rickettsiosis, ehrlichiosis, leptospirosis, bartonellosis and tuberculosis; as well on viral diseases such as dengue, Lassa fever and Chikungunya. Section II includes topics covering protozoan diseases such as malaria, toxoplasmosis, amebiasis, leishmaniasis and Chagas disease; as well on helminthic diseases such as echinococcosis/hidatidosis, taeniosis/cysticercosis, schistosomiasis, filariasis, strongyloidiasis and soil-transmitted helminths. Section III includes topics on multiple-etiology conditions such as sexually transmitted diseases, new diagnostic tools for tropical diseases and vector-borne diseases; also includes non-infectious

This books does not intend to be an exhaustive compilation and this first edition has included not just multiple different topics but also a wide geographical participation from many countries where tropical medicine is of interest. Its online availability

conditions particularly related to childhood health in the tropics.
