*Edited by Luis Rodrigo*

Cholangiocarcinoma is a type of malignant tumor that affects the biliary system. It can arise anywhere in the bile ducts, manifesting itself as obstructive jaundice. It has an annual incidence of 1–2 cases per 100,000 people. One variety of the disease, the Klatskin tumor, occurs in the hepatic hilum and is characterized by poor prognosis. Generally, cholangiocarcinomas are slow-growing tumors with late metastases. Localized tumors are treated surgically, but intervention is discouraged when they are extensive. The disease affects both sexes, but most cases occur in patients aged over 60 years. Primary sclerosing cholangitis, chronic biliary infection, and choledochal cysts are associated with an increased risk of cholangiocarcinoma.

ISBN 978-1-78923-875-4

Bile Duct Cancer

Published in London, UK © 2019 IntechOpen © wildpixel / iStock

## Bile Duct Cancer

*Edited by Luis Rodrigo*

## Bile Duct Cancer

*Edited by Luis Rodrigo*

Published in London, United Kingdom

### *Supporting open minds since 2005*

Bile Duct Cancer http://dx.doi.org/10.5772/intechopen.78186 Edited by Luis Rodrigo

#### Contributors

Toshifumi Wakai, Pankaj Prasoon, Kohei Miura, Kizuki Yuza, Yuki Hirose, Jun Sakata, Ahmad A Madkhali, Faisal Al-Alem, Marco Massani, Tommaso Stecca, Bruno Pauletti, Ezio Caratozzolo, Luca Bonariol, Adrian Bartos, Andrei Herdean, Dana Monica Bartos, Gustavo Gomez, Fernando Hernandez, Nicolae Bacalbasa, Irina Balescu, Luis Rodrigo, Adolfo Suarez

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First published in London, United Kingdom, 2019 by IntechOpen IntechOpen is the global imprint of INTECHOPEN LIMITED, registered in England and Wales, registration number: 11086078, The Shard, 25th floor, 32 London Bridge Street London, SE19SG – United Kingdom Printed in Croatia

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Bile Duct Cancer Edited by Luis Rodrigo p. cm. Print ISBN 978-1-78923-875-4 Online ISBN 978-1-78923-876-1 eBook (PDF) ISBN 978-1-83962-215-1
