**Funding**

The first author was the recipient of the Carnegie Post-Doctoral Fellowship award.

## **Author details**

Ruchika Meel1 \* and Ricardo Gonçalves2

1 Division of Cardiology, Chris Hani Baragwanath Academic Hospital and University of the Witwatersrand, Johannesburg, South Africa

2 Olivedale and Glynnwood Hospitals, Johannesburg, South Africa

\*Address all correspondence to: ruchikameel@gmail.com

© 2019 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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