Acknowledgements

chemical composition that contains several antioxidant groups, especially phenolic

Ethanolic fruit extracts were evaluated for the diuretic activity on individual rat through the control of the parameters, total urine volume, and urine concentration

The immunity activities of crude hot water-soluble polysaccharide (PS) were evaluated using the carbon clearance test and serum hemolysin analysis in mice. The PS (500 mg/kg) had a significant increase in the clearance rate of carbon

Fig aqueous-ethanolic extract was investigated for antispasmodic effect (suppression of muscle spasms) on rabbit jejunum preparations. The extracts

contractions and with insignificant effect on high K<sup>+</sup> (80 mM). Similar results were observed with cromakalim, a potassium channel-opening vasodilator. This spasmo-

Proteases derived from fig aqueous-ethanolic extract were investigated on human blood coagulation using ex vivo model of human platelets from volunteers free of medications for 1 week. Extracts at 0.6 and 1.2 mg/mL repressed the human

(ADP). Ficin, a mixture of proteases derived from figs, seems to be responsible for the activation of blood coagulation factor X (vitamin K-dependent plasma

Since ancient times, the fruits and leaves of F. carica have been used as food and for their different therapeutic effects. In recent years several scientific works have analyzed the chemical composition of both parts of the plant to know more in depth the phytochemical compounds responsible for the biological properties

(25 mM)-induced

ATP


(0.1–3.0 mg/mL) produced relaxation of spontaneous and low K<sup>+</sup>

lytic activity of F. carica fruits is probably due to the activation of K+

platelet aggregation with the agonists adrenaline and adenosine 5<sup>0</sup>

glycoprotein with pivotal role in hemostasis) [2, 6, 38].

treatment in rats based on the increase in urine volume and cation and anion

, and Cl�. Results showed a marked diuresis of ethanolic fruit extract

compounds such as flavonoids and flavonols [7].

particles and serum hemolysin level of normal mice [6].

3.14 Diuretic activity

3.14.1 Fruit extracts

Modern Fruit Industry

, K<sup>+</sup>

excretions [6].

3.15 Immunity activity

3.16 Antispasmodic activity

3.15.1 Fruit extracts

3.16.1 Fruit extracts

channels [2, 6].

3.17.1 Fruit extracts

4. Conclusions

128

3.17 Antiplatelet activity

of Na<sup>+</sup>

This work received financial support from the project INTERREG—MD.Net: When Brand Meets People. R. Rodríguez-Solana acknowledges the financial support from the Foundation for Science and Technology, Portugal (Grant SFRH/BPD/ 103086/2014).
