**Part 3 Pharmacology 169**

Chapter 9 **Approaches for Searching of Modified Steroid Estrogen Analogues with Improved Biological Properties 171**  Alexander Shavva, Svetlana Morozkina and Olga Galkina

Chapter 10 **Drug Design Approaches to Manipulate the Agonist-Antagonist Equilibrium in Steroid Receptors 221**  Scott J. Lusher, Paolo Conti, Wim Dokter, Pedro H. Hermkens and Jacob de Vlieg
