**4. Enzymes participating in the synthesis of steroid hormones**

The synthesis of the numerous enzymes participating in steroid hormones synthesis is under the stimulatory effects of hormones secreted by the pituitary ACTH, LH and follicle stimulating hormone (FSH). Other pituitary hormones, such as growth hormone (GH) and prolactin (PRL), also play a role regulating the synthesis of some of these enzymes.

Based on the progression of changes occurring to the cholesterol molecule, four enzymes seem to be crucial for hormone synthesis: cytochrome P-450scc, 3β-hydroxysteroid dehydrogenase/Δ5-4-isomerases (3β-HSDs), 17 α-Hydroxylase/17,2O-desmolase, and aromatase cytochrome P450
