**5.3.2 Obestatin**

Produced in the stomach and other tissues, obestatin is one of the metabolic hormones that has effects on systems other than the digestive system. In *in vitro* porcine granulosa cells, obestatin increases the secretion of progesterone, without modifying testosterone or estradiol secretion (Mészárosová et al., 2008). Thus, it is possible that obestatin stimulates StAR phosphorylation without affecting the activity of the enzymes participating in androgen synthesis.
