**5.5.3 Dopamine**

Human granulosa cells (GCs) express 4 out of 5 dopamine (DA) receptors (D1 and D5 coupled and linked to cAMP increase, D2 and D4; Gi/Gq coupled and linked to IP3/DAG. *In vitro*, the stimulation of human granulosa cells with hCG did not increase mRNA or protein levels of DA receptors. D1 and D2 receptors are also present in the ovaries of rats (Rey-Ares et al., 2007).
