**9. Therapeutics**

In the individuals with type 1 leprosy reactions (reversal reaction), the systemic administration of corticosteroids (initial dose of 40–60 mg prednisolone for 14 days, than gradually increase by 5 mg every 14 days).

Type 2 reaction is treated with the administration of thalidomide (100–400 mg/ per day) plus the administration of systemic corticosteroids most commonly prednisolone 40 mg for 5 days [13].

In the case of syn. Lucio's phenomenon (type 3 reaction) the use of systemic corticosteroids are the first choice (**Figure 5**).

In the patient with nerve damage, it is necessary to incorporate active and passive physical therapy, local skin care if acral mutilations are present. Certain individuals require orthopedic prosthesis as well as reconstructive procedure(s) (nose reconstruction, tarsorrhaphy, hand surgery, etc.) [13].
