**6. Conclusion**

Liposomes appear to be reputed carriers for various chemical and macromolecular species. From way back their discovery, liposomes have been subject to extensive evolution, in terms of composition, manufacturing and usages, which led to several openings in both basic and applied life sciences. The general details presented herein attempted to reveal some of the existing gaps in liposomes technology and open new windows for further research. An important future breakthrough could be the discovery of cost-effective materials to formulate liposome vesicles with remarkable versatility viz., being suitable as vehicles for various molecules while holding a clear molecular architecture to act as cell models for in vitro bioassays. In addition, novel manufacturing methods for facile encapsulation of both hydrophobic and hydrophilic molecules with no need for organic solvents and special equipment or sophisticated infrastructures are highly desired. Furthermore, the critical issue of system instability for liposomes loaded with hydrophilic materials requires new strategies that will achieve acceptable loading while aiming at targeting cargo delivery at the site of interest. Finally, since liposomes have demonstrated some clinical success as drug vehicles, future efforts should be dedicated to ensuring wider developments and implementation of therapeutic liposomes. This would enhance commercial availability and accessibility of liposome products across the globe, particularly in low- and middle-income countries.
