**Author details**

Samuel King and Cenk Suphioglu\* NeuroAllergy Research Laboratory (NARL), School of Life and Environmental Sciences, Deakin University, Geelong, Victoria, Australia

\*Address all correspondence to: cenk.suphiolgu@deakin.edu.au

© 2020 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

**31**

*An Alternate View of Neuroprotection with Peptides in Alzheimer's Disease*

disease. Alzheimer's & Dementia: Translational Research & Clinical Interventions. 2016;**2**(2):99-109. DOI:

[9] Sarlus H, Heneka MT. Microglia in Alzheimer's disease. Journal of Clinical Investigation. 2017;**127**(9):3240-3249.

10.1016/j.trci.2016.05.001

DOI: 10.1172/JCI90606

pubmed/28127589

2014;**79**:1-12

1907;**64**:146-148

s00401-018-01957-y

2019;**575**:669-673

[14] Ising C, Venegas C, Zhang S, Scheiblich H, Schmidt SV, Vieira-Saecker A, et al. NLRP3 inflammasome activation drives tau pathology. Nature.

[15] Götz J, Streffer JR, David D,

disease and related disorders:

Schild A, Hoerndli F, Pennanen L, et al. Transgenic animal models of Alzheimer's

[10] Kempuraj D, Thangavel R, Natteru PA, Selvakumar GP, Saeed D, Zahoor H, et al. Neuroinflammation Induces Neurodegeneration. Journal of Neurology, Neurosurgery and Spine. 2016;**1**(1):1003. Available from: https://www.ncbi.nlm.nih.gov/

[11] Lyman M, Lloyd DG, Ji X, Vizcaychipi MP, Ma D.

Zeitschrift für Psychiatrie und psychisch-gerichtliche Medizin.

Neuroinflammation: The role and consequences. Neuroscience Research.

[12] Alzheimer A. Über eine eigenartige Erkrankung der Hirnrinde. Allgemeine

[13] Stancu IC, Cremers N, Vanrusselt H, Couturier J, Vanoosthuyse A, Kessels S, et al. Aggregated Tau activates NLRP3– ASC inflammasome exacerbating exogenously seeded and nonexogenously seeded tau pathology in vivo. Acta Neuropathologica. 2019;**137**(4):599-617. DOI: 10.1007/

*DOI: http://dx.doi.org/10.5772/intechopen.91065*

[1] Barnham KJ, Masters CL, Bush AI. Neurodegenerative diseases and oxidative stress. Nature Reviews. Drug Discovery. 2004;**3**(3):205-214. DOI:

[2] Nopoulos PC. Huntington disease: A single-gene degenerative disorder of the striatum. Dialogues in Clinical Neuroscience. 2016;**18**(1):91-98. Available from: https://www.ncbi.nlm.

[3] Jucker M, Walker LC. Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders. Annals of Neurology. 2011;**70**(4):532- 540. Available from: https://www.ncbi. nlm.nih.gov/pubmed/22028219

[4] Verma M, Vats A, Taneja V. Toxic species in amyloid disorders: Oligomers or mature fibrils. Annals of Indian Academy of Neurology. 2015;**18**(2):138-145. Available from: https://www.ncbi.nlm.nih.gov/

[5] Soto C. Unfolding the role of protein misfolding in neurodegenerative diseases. Nature Reviews Neuroscience.

2003;**4**(1):49-60. DOI: 10.1038/

activation in brain aging and

nih.gov/pubmed/19840553

[6] Lucin KM, Wyss-Coray T. Immune

neurodegeneration: Too much or too little? Neuron. 2009;**64**(1):110-122. Available from: https://www.ncbi.nlm.

[7] Venegas C, Heneka MT. Dangerassociated molecular patterns in Alzheimer's disease. Journal of

Leukocyte Biology. 2017;**101**(1):87-98. DOI: 10.1189/jlb.3MR0416-204R

[8] Van Eldik LJ, Carrillo MC, Cole PE, Feuerbach D, Greenberg BD, Hendrix JA, et al. The roles of inflammation and immune mechanisms in Alzheimer's

pubmed/26019408

nrn1007

nih.gov/pubmed/27069383

10.1038/nrd1330

**References**

*An Alternate View of Neuroprotection with Peptides in Alzheimer's Disease DOI: http://dx.doi.org/10.5772/intechopen.91065*
