**Author details**

Peeradon Tuntiteerawit, Tichakorn Singto, Anupon Tadee and Supatra Porasuphatana\* Faculty of Pharmaceutical Sciences, Division of Pharmacognosy and Toxicology, Khon Kaen University, Khon Kaen, Thailand

\*Address all correspondence to: psupatra@kku.ac.th

© 2019 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

**279**

*Modulation of Edible Plants on Hepatocellular Carcinoma Induced by Aflatoxin B1*

[9] Lavkor I, Var I. The control of aflatoxin contamination at harvest, drying, pre-storage ad storage periods in peanut: The new approach. In: Abdulra'Uf L, editor. Aflatoxin Control, Analysis, Detection and Health Risks. Rijeka: IntechOpen; 2017. pp. 45-65. DOI: 10.5772/intechopen.68675

[10] Sanlier N, Guler SM. The benefits of Brassica vegetables on human health. Journal of Human Health Research.

[11] Kensler TW, Egner PA, Wang JB, Zhu YR, Zhang BC, Lu PX, et al. Chemoprevention of hepatocellular carcinoma in aflatoxin endemic areas. Gastroenterology. 2004;**127** (5 Suppl):310-318. DOI: 10.1053/j.

[12] Herr I, Büchler MW. Dietary constituents of broccoli and other cruciferous vegetables: Implications for prevention and therapy of cancer. Cancer Treatment Reviews. 2010;**36**(5):377-383. DOI: 10.1016/j.

[13] Wallig MA, Heinz-Taheny KM, Epps DL, Gossman T. Synergy among phytochemicals within crucifers: Does it translate into chemoprotection?

[14] Dashwood RH, Arbogast DN, Fong AT, Pereira C, Hendricks JD, Bailey GS. Quantitative inter-relationships between aflatoxin B1 carcinogen dose, indole-3-carbinol anti-carcinogen dose, target organ DNA adduction and final tumor respose. Carcinogenesis. 1989;**19**(1):175-181. DOI: 10.1093/

[15] Dashwood RH. Indole-3-carbinol: Anticarcinogen or tumor promoter in brassica vegetables? Chemico-Biological

The Journal of Nutrition. 2018;**135**(12):2972S-2977S. DOI:

10.1093/jn/135.12.2972S

carcin.10.1.175

2018;**1**(1):104

gastro.2004.09.046

ctrv.2010.01.002

*DOI: http://dx.doi.org/10.5772/intechopen.87296*

[1] International Agency for Research on Cancer. Cancer Today: Estimated Number of Deaths in 2018, Worldwide, Both Sexes, all Ages. 2018. Available from: http://gco.iarc.fr/today/onlineanalysis [Accessed: March 30, 2019]

[2] Balogh J, Iii D, Asham E,

10.14218/JCTH.2015.00025

2013007166

10.1093/toxsci/kfq283

Burroughs S, Boktour M, Saharia A, et al. Hepatocellular carcinoma: A review. J Hepatocell Carcinoma. 2016;**3**:41-53. DOI: 10.2147/JHC.S61146

[3] Chitapanarux T, Phornphutkul K. Risk factors for the development of hepatocellular carcinoma in Thailand. Journal of Clinical and Translational Hepatology. 2015;**3**(3):182-188. DOI:

[4] International Agency for Research on Cancer. Chemical Agents and Related Occupations. Lyon: WHO; 2009. 599 p

[6] Kensler TW, Roebuck BD, Wogan GN, Groopman JD. Aflatoxin: A 50-year odyssey of mechanistic and translational toxicology. The Journal of Toxicological Sciences. 2011;**120**(S1):S28-S48. DOI:

[7] Bbosa GS, Kitya D, Odda J, Ogwal-Okeng J. Aflatoxins metabolism. Health (Irvine Calif). 2013;**05**(10):14-34

[8] Kumar P, Mahato DK, Kamle M, Mohanta TK, Kang SG. Aflatoxins: A global concern for food safety, human health and their management. Frontiers in Microbiology. 2017;**7**:2170. DOI:

10.3389/fmicb.2016.02170

[5] Moudgil V, Redhu D, Dhanda S, Singh J. A review of molecular mechanisms in the development of hepatocellular carcinoma by aflatoxin and hepatitis B and C viruses. Journal of Environmental Pathology, Toxicology and Oncology. 2013;**32**(2):165-175. DOI: 10.1615/JEnvironPatholToxicolOncol.

**References**

*Modulation of Edible Plants on Hepatocellular Carcinoma Induced by Aflatoxin B1 DOI: http://dx.doi.org/10.5772/intechopen.87296*
