*2.7.1 Dialium guineense*

*Dialium guineense* is a fruit-bearing tree known as the velvet tamarind. Their bark, leaves, seeds, and fruit showed biological properties such as antimicrobial activities, anti-infectious diseases, and wound-healing [60, 61]. Extract from *Dialium guineense* showed ROS scavenging activities and could normalize the levels of enzyme biomarkers of hepatotoxicity: ALP, AST, and AST induced by AFB1. Furthermore, treatment of velvet tamarind extract before AFB1 exposure increased the antioxidant activities of various enzymes including SOD, GPx, GR, CAT, GSH, and oxidized glutathione (GSSH), decreased lipid peroxidation, protein carbonyl and DNA fragmentation. *In vitro* and *in vivo* experiments have also confirmed the protective effects of velvet tamarind extract against hepatotoxicity induced by AFB1 via antioxidant properties [62].
