**6. DBS in different neurodegenerative diseases**

The common form of dementia, AD, treated with lesser efficiency of success in treatment via this technique has been used to modulate nonfunctional neuronal circuits with abnormalities seen in cortical and subcortical areas of the brain. Treatment helps in altering cholinesterase inhibitors and NMDA receptor antagonist [31]. DBS is a significant option for treatment of movement disorders that are intractable to drugs namely Parkinson's disease, essential tremors, dystonia, and have recently shown to be effective against treatment of OCDs, depression, and Tourette syndrome [5, 31].
