Meet the editor

Professor Nima Rezaei obtained an MD from Tehran University of Medical Sciences, Iran, and an MSc in Molecular and Genetic Medicine and a Ph.D. in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also completed a short-term fellowship in Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital, England. Dr. Rezaei is now Full Professor of Immunology

and Vice Dean of International Affairs, School of Medicine, Tehran University of Medical Sciences, and the co-founder and Deputy President of the Research Center for Immunodeficiencies. He is also the founding president of the Universal Scientific Education and Research Network (USERN). Dr. Rezaei has been the director of more than fifty research projects and has designed and participated in several international collaborative projects. He is also an editorial assistant or board member for more than thirty international journals. He has edited more than 30 international books, has presented more than 500 lectures/posters in congresses/meetings, and has published more than 900 articles in international scientific journals.

Contents

and Production

Introduction on Monoclonal Antibodies *by Mona Sadeghalvad and Nima Rezaei*

*Rodrigo Aguiar and Tauane Pereira*

*and Kazuaki Muranaka*

Management - An Update

*by Hanley N. Abramson*

Antibodies

**Preface XI**

**Chapter 1 1**

**Chapter 2 23**

**Chapter 3 43**

**Chapter 4 81**

**Chapter 5 107**

**Chapter 6 127**

**Chapter 7 139**

Therapeutic Applications of Monoclonal Antibodies in Urologic-Oncology

Emerging Monoclonal Antibodies for the Treatment of Multiple Myeloma

Alternative Methods to Animal Use for Monoclonal Antibody Generation

Monospecific and Polyreactive Monoclonal Antibodies against Human

Analytical Characterization of Monoclonal Antibodies with Novel Fc

*In silico* Techniques for Prospecting and Characterizing Monoclonal

*by Tania M. Manieri, Carolina G. Magalhaes, Daniela Y. Takata,* 

*by Maya Kulshekar, Shridhar C. Ghagane, Sridevi I. Puranik,* 

*by Atis Chakrabarti, Jukka Kervinen, Egbert Müller, Toru Tanaka* 

*by Jane Zveiter de Moraes, Barbara Hamaguchi, Camila Braggion, Enzo Speciale, Fernanda Cesar, Gabriela Soares, Juliana Osaki,* 

Leukocyte Antigen-E: Diagnostic and Therapeutic Relevance

*by Mepur H. Ravindranath and Fatiha E.L. Hilali*

Receptor-Based Chromatography Technique

*João V. Batalha-Carvalho and Ana M. Moro*

*Rajendra B. Nerli and Murigendra B. Hiremath*
