**Chapter 6**

*Alginates - Recent Uses of This Natural Polymer*

biodegradable devices for controlled drug delivery. International Journal of Biological Macromolecules. 2019;**135**:829-838. DOI: 10.1016/j.

mechanisms, cytotoxicity and in vitro antifungal activity. Materials Science and Engineering: C. 2019;**99**:1350-1361.

DOI: 10.1016/j.msec.2019.02.036

carbpol.2016.08.079

[60] Martínez-Gómez F, Guerrero J, Matsuhiro B, Pavez J. In vitro release of metformin hydrochloride from sodium alginate/polyvinyl alcohol hydrogels. Carbohydrate Polymers. 2017;**155**:182-191. DOI: 10.1016/j.

[61] Wang Y. Programmable hydrogels. Biomaterials. 2018;**178**:663-680. DOI: 10.1016/j.biomaterials.2018.03.008

[54] Supramaniam J, Adnan R, Kaus NHM, Bushr R. Magnetic nanocellulose alginate hydrogel beads as potential drug delivery system. International Journal of Biological Macromolecules. 2018;**118**:640-648. DOI: 10.1016/j.

[55] Shtenberg Y, Goldfeder M, Prinz H, Shainsky J, Ghantous Y, Abu El-Naaj I, et al. Mucoadhesive alginate pastes with embedded liposomes for local oral drug delivery. International Journal of Biological Macromolecules. 2018;**111**:62- 69. DOI: 10.1016/j.ijbiomac.2017.12.137

[56] Yuan N, Li S, Li G. Sodium alginate coated mesoporous silica for dual bio-responsive controlled drug delivery. Journal of Drug Delivery Science and Technology. 2018;**46**:348-353. DOI:

[57] Xie M, Zhang F, Liu L, Zhang Y, Li Y, Li H, et al. Surface modification of graphene oxide nanosheets by protamine sulfate/sodium alginate for anti-cancer drug delivery application. Applied Surface Science. 2018;**440**:853- 860. DOI: 10.1016/j.apsusc.2018.01.175

[58] Ghosal K, Das A, Sanjoy Das SK, Mahmood S, Ramadan MAM, Thomas S. Synthesis and characterization of interpenetrating polymeric networks based bio-composite alginate film: A well-designed drug delivery platform. International Journal of Biological Macromolecules. 2019;**130**:645-654. DOI: 10.1016/j.ijbiomac.2019.02.117

[59] Querobino SM, de Fariab NC, Vigatob AA, da Silvac BGM, Machadod IP, Costac MS, et al. Sodium alginate in oil-poloxamer organogels for intravaginal drug delivery: Influence on structural parameters, drug release

10.1016/j.jddst.2018.05.026

ijbiomac.2019.05.210

ijbiomac.2018.06.043

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