**Author details**

Andriy Zagayko, Tatiana Briukhanova, Dmytro Lytkin\*, Anna Kravchenko and Victoria Fylymonenko National University of Pharmacy, Kharkiv, Ukraine

\*Address all correspondence to: d.v.lytkin@gmail.com

© 2019 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

**291**

*Prospects for Using the Natural Antioxidant Compounds in the Obesity Treatment*

Animal models of metabolic syndrome: A review. Nutrition & Metabolism. 2016;**13**:65. DOI: 10.1186/

[9] Muktabhant B, Sanchaisuriya P,

10.1186/1471-2458-12-349

[10] Yajnik CS, Katre PA, Joshi SM, Kumaran K, Bhat DS, Lubree HG, et al. Higher glucose, insulin and insulin resistance (HOMA-IR) in childhood predict adverse cardiovascular risk in early adulthood: The Pune Children's Study. Diabetologia. 2015;**58**(7):1626- 1636. DOI: 10.1007/s00125-015-3602-z

[11] Maranhão RC, Carvalho PO, Strunz CC, Pileggi F. Lipoprotein (a): Structure, pathophysiology and clinical implications. Arquivos Brasileiros de Cardiologia. 2014;**103**(1):76-84. DOI:

[12] Schaefer EJ, Tsunoda F, Diffenderfer M,

Lipoproteins, Apolipoproteins, Fatty Acids, and Sterols, and Next Generation Sequencing for the Diagnosis and Treatment of Lipid Disorders [Internet]. 2016. Available from: https://www. ncbi.nlm.nih.gov/books/NBK355892/

[13] Nair AB, Jacob S. A simple practice guide for dose conversion between animals and human. Journal of Basic and Clinical Pharmacy. 2016;**7**(2):27-31.

[14] Bang H, Davidian M. Experimental statistics for biological sciences. Methods

DOI: 10.4103/0976-0105.177703

Polisecki E, Thai N, Asztalos B. The Measurement of Lipids,

10.5935/abc.20140101

[Accessed: 2016-05-29]

Sarakarn P, Tawityanon W, Trakulwong M, Worawat S, et al. Use of glucometer and fasting blood glucose as screening tools for diabetes mellitus type 2 and glycated haemoglobin as clinical reference in rural community primary care settings of a middle income country. BMC Public Health. 2012;**12**:349. DOI:

s12986-016-0123-9

*DOI: http://dx.doi.org/10.5772/intechopen.83421*

[1] Hruby A, Hu FB. The epidemiology

PharmacoEconomics. 2015;**33**(7):673- 689. DOI: 10.1007/s40273-014-0243-x

[2] Manna P, Jain SK. Obesity, oxidative stress, adipose tissue dysfunction, and the associated health risks: Causes and therapeutic strategies. Metabolic Syndrome

and Related Disorders. 2015;**13**(10): 423-444. DOI: 10.1089/met.2015.0095

DOI: 10.1016/j.bj.2017.06.007

[3] Hurrle S, Hsu WH. The etiology of oxidative stress in insulin resistance. Biomedical Journal. 2017;**40**(5):257-262.

[4] Henriksen EJ, Diamond-Stanic MK, Marchionne EM. Oxidative stress and the etiology of insulin resistance and type 2 diabetes. Free Radical Biology & Medicine. 2010;**51**(5):993-999. DOI: 10.1016/j.freeradbiomed.2010.12.005

[5] Gradinaru D, Borsa C, Ionescu C, Prada GI. Oxidized LDL and NO synthesis—Biomarkers of endothelial dysfunction and ageing. Mechanisms of Ageing and Development. 2015;**151**:101- 113. DOI: 10.1016/j.mad.2015.03.003

[6] Vincent HK, Bourguignon CM, Weltman AL, Vincent KR, Barrett E, Innes KE, et al. Effects of antioxidant supplementation on insulin sensitivity, endothelial adhesion molecules, and oxidative stress in normal-weight and overweight young adults.

Metabolism: Clinical and Experimental. 2009;**58**(2):254-262. DOI: 10.1016/j.

[7] Wang S, Moustaid-Moussa N, Chen L, Mo H, Shastri A, Sui R, et al. Novel insights of dietary polyphenols and obesity. The Journal of Nutritional Biochemistry. 2014;**25**(1):1-18. DOI: 10.1016/j.jnutbio.2013.09.001

[8] Wong SK, Chin KY, Suhaimi FH, Fairus A, Ima-Nirwana S.

metabol.2008.09.022

of obesity: A big picture.

**References**

*Prospects for Using the Natural Antioxidant Compounds in the Obesity Treatment DOI: http://dx.doi.org/10.5772/intechopen.83421*
