**8. Conclusions**

The free radicals are normally synthesized during metabolic reactions in the cells and disease. These free radicals are removed by various scavenging activities of cellular and noncellular antioxidants. The imbalance of excess ROS formation and diminished activity of antioxidants results in the formation of oxidative stress which is linked with various pathological chronic conditions like cardiovascular, neurodegenerative, and renal disorders.
