**4.6 Assessment of the catalase activity in testicular and epididymal tissues of male Wistar rats subjected to various treatments**

A significantly lower CAT activity was observed in testicular tissue of STZ-induced diabetic rats (**Table 1**) in comparison to nondiabetic rats (12.21 ± 1.235 μmol/mg versus 18.00 ± 1.524 μmol/mg, p < 0.05). The supplementation of KV to nondiabetic rats (N + KV) did not significantly affect testicular CAT activity in comparison to the untreated nondiabetic group. KV treatment of diabetic rats elevated testicular CAT activity in comparison to diabetic control, and CAT activity was restored to normalcy. Likewise, a significantly higher testicular CAT activity was observed after insulin treatment in diabetic rats (D + IN) when compared to the diabetic control rats.

As shown in **Table 1**, STZ-induced diabetic rats showed significantly lower CAT activity in epididymal tissue compared to the N group (2.864 ± 0.415 μmol/mg versus 6.162 ± 0. 612 μmol/mg, p < 0.05). There was no significant difference in the epididymal CAT activity of rats supplemented with KV (N + KV) when compared to the N group. The separate treatment of diabetic rats with KV and insulin significantly elevated CAT activity in the epididymis compared to the diabetic controls.
