**4.2 Ondansetron to facilitate ORT**

Children who received oral ondansetron initially were less likely to be administered IV rehydration compared with those given placebo. In addition, both oral and IV ondansetron administration are associated with reduced rate of hospitalization [17]. Ondansetron is contraindicated in children with long QT syndrome, concomitant drugs that prolong QT, and to be used cautiously in children with heart disease.
