*2.2.3 Hypodontia and delayed dental development*

Tan et al. found that the presence and extent of hypodontia in CLP patients did not influence the dental development [28]. This contrasted with earlier studies [20, 24] that found a bigger delay in dental development in clefts with hypodontia than without hypodontia, and the more severe the hypodontia, the bigger the delay. However, these studies had several confounding factors. Ranta's study only included patients with isolated cleft palate [24], while the study of Lai et al. included various cleft types [20].
