Meet the editor

Prof Dr Gamal Abdul Hamid received his German Board certification in internal medicine and his PhD in hematology-oncology from the Faculty of Medicine (Caral Gustav Carus), University of Dresden from 1987 to 1993. Currently, he is working as the Director of the National Program of Cancer Control in Yemen and he is the head of hematology and clinical laboratory in the Faculty of Medicine, University of Aden. He is the General Secre-

tary of the Yemen Cancer Society and founder of Aden Cancer Registry. He is serving as an editorial member of several journals, has authored or co-authored many articles in a great variety of journals and has delivered lectures at many conferences and institutions in Yemen and internationally and has also reviewed national and international journals. He is a member of European Society for Medical Oncology (ESMO), American Society of Clinical Oncology (ASCO), International Network For Cancer Treatment and Research (INCTR), and Pan Arab Oncology.

Contents

**Preface III**

**Chapter 1 1**

**Chapter 2 11**

**Chapter 3 31**

**Chapter 4 57** miRNAs in Acute Lymphoblastic Leukemia: Diagnosis, Prognosis and Target

**Chapter 5 73**

**Chapter 6 99**

**Chapter 7 119**

**Chapter 8 137**

*by Xiaoxiao Yang, Xuewen Xu, Yanfang Liu, Aihua Gong, Dongqing Wang,* 

Pediatric Acute Lymphoblastic Leukemia: Recent Advances for a Promising

*by Yazmín Gómez-Gómez, Jorge Organista-Nava, Berenice Illades-Aguiar* 

New Protein Markers of Chronic Lymphocytic and Acute Lymphocytic

Chronic Lymphocytic Leukemia: Rapidly Changing Treatment Landscape

Perceptions and Challenges for Adoption of Generics and Biosimilars in

*by Martina Maďarová, Dominik Dobransky and Tomas Dobransky*

*by Yazan Samhouri, Rupin Shah and Cyrus Khan*

Target Therapy in Hematological Malignancies

*by Amit Garg, Deepak CSN and Tarveen Jandoo*

*by Safa Shukry, Fadhel Hariri and Abdul Wahab Al-Nehmi*

Introductory Chapter: Advances in Hematologic Malignancies

*by Gamal Abdul Hamid and Fadhel Hariri*

*by Sneha Tandon and Angela S. Punnett*

*and Marco Antonio Leyva-Vázquez*

*Xiang Liao and Haitao Zhu*

Future

Therapeutic

Leukemia

Oncology

Advances in Acute Myeloid Leukemia Stem Cells
