**4.1 Details of HBO therapy**

After receiving routine clinical care on day 0 (the day of HSPC infusion), subjects were exposed to HBO for a total of 90 min after compression to 2.5 atmosphere absolutes (ATA) in a monoplace hyperbaric chamber (Model 3200/3200R, Sechrist Industries, Inc., USA), breathing 100% oxygen. The subjects spent 10–15 min during the compression and decompression phases and 10 min room air breaks for every 30 min of HBO treatment.
