**Conflict of interest**

We would like to declare there is no conflict for this work**.**

*Genetic Polymorphisms DOI: http://dx.doi.org/10.5772/intechopen.88063*

*The Recent Topics in Genetic Polymorphisms*

genetic factors. From these diseases is behavioral genetics neuropsychiatric, such as schizophrenia, depression in which a genetic fault transferred from parents to sons through familial genes causing elevated the risk of a particular disease. SNPs can affect more than 90% of genetic variation and are responsible for the occurrence of differences between the humans. Despite the presence of SNPs, there is no relation to modify or change cellular function that is to say have no effects, and at the same time, many SNPs were found to participate in the initiation of disease like cancer or act as prophylaxis against a certain disease or even impact the responses to medications. Depending on the SNPs' position in the genome, we can classify them into that happen with exome (coding region), intron (non-coding region), and between adjacent genes (intergenic region). Because there is much of non-coding DNA (99%) that lead to harboring majority of SNPs occurring in these segments. However, only small part (1%) of genome is considered important to represent exome that can contribute existing mutations, and SNPs that have a big outcome on several diseases. Non-coding genome includes many categories of regulatory factors such as promoters, enhancers, silencers, and insulators. Each one of them provides binding sites for proteins, carries out transcription, activates transcription, sup-

presses transcription, and controls transcription process, respectively.

are genotyping and scanning sequence, respectively.

in ways that I never knew that I needed.

**Acknowledgements**

my publishing team."

**Conflict of interest**

SNPs are very important and used in various studies such as estimating the tendency to disease and predicting genetic lesion; and are also used as biomarkers since they can occur near disease genes for complicated diseases, but not always. In complex disease, which means a pathological circumstance of the body due to a defect in a number of genetic and environmental aspect, SNP can affect that person has toward a specific disease. Nowadays, various methods have been established and assembled to identify known or unknown SNPs through two categories which

I am grateful to my family, father, mother, sisters, and brothers, for always being the person I could turn to during those dark and desperate years. They sustained me

I have to start by thanking my wife, and my daughter awesome, from reading early drafts to giving me the support. Thank you so much. "Thanks to everyone in

We would like to declare there is no conflict for this work**.**

**10**
