**2. Causes**

The childhood nephrotic syndrome is principally idiopathic or primary, though a limited number of cases are secondary to glomerular and inclusive diseases and other infectious agents. Age reliant is also the etiology factor of nephrotic syndrome. Maximum cases presenting in the first 3 months of lifespan are mentioned as CNS (congenital nephrotic syndrome) and are caused by genetic diseases. While in the remaining of the first year of lifecycle (3–12 months) there has been no effective study of the etiology of nephrotic syndrome reported cases, there are a number of stats shows that up to 40% of reported cases meanwhile this time may also be due to genetic factors [1]. At the time of first year and in the first decade of life, maximum presenting cases are due to primary or idiopathic nephrotic syndrome, at the time of first 10 years of lifecycle the number of secondary nephrotic syndrome cases increases.
