Meet the editors

 Mike Barbeck has 17 years of experience in regenerative biomedical research working at institutes in Germany. He works on research into the principles of biomaterial-mediated tissue regeneration, which has resulted in 62 papers in peer-reviewed journals and a variety of congress distributions. His research has led to further elucidation of cellular fundamentals of the foreign body response to different biomaterials with special focus on the

role and differentiation of macrophages and multinucleated giant cells for tissue regeneration. His key interests are tissue regeneration, bone regeneration, bone substitute materials, collagen-based biomaterials, inflammatory cell/tissue responses to biomaterials, degradation of biomaterials, tissue responses to biomaterials, macrophages and wound healing, and biocalcification.

Ole Jung studied medicine at the University Medical Center Hamburg-Eppendorf with stays abroad in the USA, Great Britain, Poland, and Switzerland. He finished his medical doctorate on biodegradable magnesium implants in 2016. Since 2011, he has been conducting research on magnesium materials for medical applications, biocompatible coatings, and dental implants.

Ralf Smeets, MD, DDS, PhD, is the Vice Head of the Department of Oral and Maxillofacial Surgery and the Head of the Division of "Regenerative Orofacial Medicine" at the University Medical Center Hamburg-Eppendorf, Germany. His academic career started in Aachen at RWTH Aachen University, where he completed his chemical studies in 1995 and studied medicine until 2003. Besides his medical studies, he studied economics at the

University of Hagen. He finished his residency as an oral- and maxillofacial surgeon and oral surgeon in 2009. In 2011, he became a full W2 professor at the Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, and was a visiting professor at University Bremerhaven (Germany) until 2015. Recently, he has been awarded an exclusive W3 Heisenberg Professorship at the University Medical Center Hamburg-Eppendorf and is the Scientific Director of the curriculum "Dental Regeneration Specialist."

Tadas Koržinskas is an oral surgeon and a certified specialist in esthetic, reconstructive dentistry and temporomandibular disorder (TMD), with 15 years of experience in oral implantology. As an international lecturer, he is recognized in the field of implant-supported restorations and TMD. His research focuses on dental implants, biomaterials, and dental occlusion.

**Preface III**

Biomaterial Processing Techniques **1**

**Chapter 1 3**

**Chapter 2 25**

**Chapter 3 37**

**Chapter 4 73**

Tissue Regeneration Concepts **91**

**Chapter 5 93**

*by Patrick Rider, Željka Perić Kačarević, Sujith Retnasingh, Said Alkildani,* 

Synthesis of Nanostructured Hydroxyapatite via Controlled

*by Andrea Ruffini, Simone Sprio, Lorenzo Preti and Anna Tampieri*

Dentin Materials as Biological Scaffolds for Tissue Engineering *by Masaru Murata, Naoto Okubo, Mamata Shakya, Md Arafat Kabir, Kenji Yokozeki, Bowen Zhu, Masahiro Ishikawa, Ryuji Kitamura* 

Advanced Surface Treatments on Titanium and Titanium Alloys Focused on Electrochemical and Physical Technologies

*by Elena Fuentes, Sofia Alves, Ainara López-Ortega, Lucía* 

Application of Bone Substitutes and Its Future Prospective

*by Ujjwal Ranjan Dahiya, Sarita Mishra and Subia Bano*

**Section 1**

Hydrothermal Route

Contents

*and Toshiyuki Akazawa*

for Biomedical Applications

*Ole Jung and Mike Barbeck*

in Regenerative Medicine

Bioprinting

**Section 2**

*Mendizabal and Virginia Sáenz de Viteri*
