**3. Autograft**

The autologous bone grafting as the name suggests 'auto' (self) involves taking up tissue from one anatomical location and transplanting it to another in the same patient. The method dates back to 1821 when Walther repaired the holes in a patient's skull using the original bone plug [11, 12]. The method is still considered to be a 'gold standard 'as there is no immunogenic response against patient's own tissue [13]. Thus, no graft rejection or histocompatibility issues are conferred. Moreover, it manifests the properties of an ideal bone graft, that is, osteogenesis, osteoinduction, and osteoconduction. However, it is not a straightforward path to follow and comes with a set of limitations associated with it. This includes an additional operative pain at donor site, increased blood loss, and also possible injury to nearby blood vessels. Besides, the inappropriate availability of tissue amount especially from infants and older patients results in added trouble [14, 15].
