**4. Conclusions**

 We report evidences from our previous work which indicates the chondroinductive capacity of newly developed biomaterials including heparin-, chondroitin sulfate-, decorin-, and poly(ε-caprolactone)-based self-assembling peptide composite scaffolds. In particular, we demonstrated that these biomimetic biomaterials fostered re-differentiation of expanded human articular chondrocytes as well as adipose-derived stem cells into chondrogenic lineage commitment. Moreover, both biological and biomechanical properties obtained of these cartilage substitutes were comparable to natural samples of chicken and calf counterparts. This clearly suggest that these newly class of biomaterials are promising for their future application in reparative and regenerative medicine platforms.
