**5.3 Abnormal immune response**

The entrance of fetal cells into the maternal circulation remains in the circulation without rejection due to weak immunogenic paternal haplotype of chorionic cell. If these cells lodge into the cardiac tissue, immune response may be triggered. The raised titres of immunoglobulins and other autoantibodies in patients with PPCM are suggestive of abnormal immune response, whereas other studies found no significant difference in levels of immunoglobulins and other autoantibodies in PPCM and control group of patients [12, 16].
