**8. Conclusions**

Based on the above, we can conclude that PDT treatment is highly recommended to strengthen antibacterial therapies. The PDT generates unspecific photo-oxidative effects that improve an effective elimination of *S. aureus* strains without generation of resistance. The information presented here could help develop standardized protocols for managing infections caused by *S. aureus*, particularly those with antimicrobial resistance. We believe it is necessary to expand future studies of this therapy *in vivo,* including clinical trials since, according to what has been presented, there are several *in vitro*, *in vivo,* and *ex vivo* evidence that proves that PDT is secure and its bactericidal effect does not produce resistance.
