**6. Summary and future directions**

**Table 1** summarizes the current state of NRP in the various fields of clinical DCD organ transplantation. The application of post-mortem NRP appears particularly relevant and advantageous in DCD kidney, liver, and heart transplantation, and the future will tell if it can have impact the fields of DCD pancreas and lung transplantation, as well. Some ethical concerns remain surrounding its use, primarily in the context of cDCD, and clear and effective steps need to always be taken to ensure lack of reperfusion of the brain and brainstem once NRP has been initiated. Through these measures and continued dialog with both intensive care as well as extra- and intrahospitalary emergency medical professionals, the hope is that the use of NRP and, thereby, DCD organ transplantation in general may be expanded to offer more organs and ones of better quality to a greater number of patients with end-stage organ disease.


#### **Table 1.**

*Clinical results observed to date with application of normothermic regional perfusion in donation after circulatory death organ transplantation.*

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**Author details**

provided the original work is properly cited.

Amelia J. Hessheimer and Constantino Fondevila\*

\*Address all correspondence to: cfonde@clinic.cat

*Normothermic Regional Perfusion in Solid Organ Transplantation*

*DOI: http://dx.doi.org/10.5772/intechopen.84771*

© 2019 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium,

General and Digestive Surgery, Digestive and Metabolic Disease Institute (ICMDM), Hospital Clínic, CIBERehd, IDIBAPS, University of Barcelona, Spain
