**16. Conclusions**

LT has been established as the gold standard treatment for patients with ESLD and following successful postoperative course, organs previously affected return to normal functionality in due time. Postoperative ICU stay is often imperative, especially in cases of adverse events during operation, delayed cardiovascular resuscitation, utilization of marginal donors, and distant organ dysfunction. Early recognition, evaluation, and treatment of hemodynamic instability, distant organ complications, impaired graft functionality, and use of optimal immunosuppressive agents are of paramount importance.

Prompt recognition and treatment of life-threatening sequelae following LT in addition with optimal management of immunosuppression are keys to successful postoperative care and have led to improved overall survival although recipients are in relatively worse condition and the use of marginal donors is more widespread.

Furthermore, overall survival of LT patients has improved dramatically in recent years due to the formation of LT specific centers and medical teams, which follow each patient from admission to the donor list up to the operation itself as well as during their postoperative course. Therefore, according to the authors, the creation of LT specific ICUs that provide a postoperative continuation of excellency in managing the intricacies of those patients is paramount. Those units will not only provide prompt treatment in cases of a complication but will also act as additional reinforcement against postoperative infections.
