**Acknowledgements**

We are grateful to the Cystic Fibrosis Foundation Patient Registry Committee for dispensing the data utilized in the illustrative application. We thank Laurie Kahill, M.S., for information regarding the process of center-specific reporting for this registry. **Tables 1**, **2** and **4** reprinted with permission of the American Thoracic Society. Copyright © 2014 American Thoracic Society [4].
