*1.3.1.1 Periodic laboratory tests*

The levels of AlAT, AspAT, GGTP, bilirubin and bile acids, the APRI index, and FibroTest are recommended. It is believed that elevated levels of at least two hepatic parameters above the norm within at least 3 months is an indication of advancing hepatic lesions. But they have low sensitivity and specificity. Most patients with multifocal cirrhosis have normal test results. Isolated elevation of aminotransferases with concurrent normal GGTP index may indicate steatosis.
