*2.1.3 Drugs and chemotherapeutic agents*

Drug-induced acute pancreatitis accounts for 21% of all cases in pediatric population. Valproic acid, radiocontrast and corticosteroids can induce pancreatitis in the context of epilepsy or inflammatory bowel diseases [4].

L-asparaginase-associated pancreatitis (AAP) occurs in 0.7–24% of children treated for acute lymphoblastic leukemia with mortality rates of 2–5%. Older children demonstrate an high risk for developing acute pancreatitis and if it occurs they could experience cancer recurrence [5].
