**5.4 Treatment**

Migrating partial seizures are usually refractory to pharmacologic treatment though some cases have responded to bromide (60–80 mg/kg/day), with a termination of the seizures for several months after almost 3 weeks of therapy [69]. Even so, one should be aware of a potential bromoderma tuberosum, which could be appearing with high doses of potassium bromide therapy [70]. Intravenous levetiracetam (60 mg/kg) rapidly interrupted migrating partial status in two children with a good tolerability and safety [71]. Other successful treatments include a combination of sodium bromide, stiripentol, and levetiracetam [72], rufinamide and acetazolamide [73, 74], and stiripentol associated with clonazepam.
