**5. Conclusion**

Primary cilia and nitric oxide are both essential for normal tissue functions. While they can operate independently of one another, often their roles and cellular pathways are complementary. While this chapter only touched on a small portion of their possible connections, scattered research suggests a more complex linkage between the two in many more organ systems and cellular pathways. However, current research on the direct links between primary cilia and NO are scarce. The aim of this chapter was to discuss the more well-known links between primary cilia and NO, and to initiate discussion leading to further examination of the topics covered. Revealing the connections between cilia and NO would provide insight into various ciliopathies and could reveal new targets for therapies.
