**Acknowledgements**

Shinya Goto acknowledges financial support from MEXT/JSPS KAKENHI 17 K19669, 18H01726, and 19H03661. SG acknowledges independent research grant support from Bristol-Myers Squibb (33999603). SG also acknowledges grant support from Vehicle Racing Commemorative Foundation and Nakatani Foundation for Advancement of Measuring Technologies in Biomedical Engineering. SG received research funding from Sanofi, Pfizer, and Ono.
