Meet the editor

Akikazu Takada was born in Japan, 1935. After graduation from Keio University School of Medicine and finishing his post-graduate studies, he worked at Roswell Park Memorial Institute NY, USA. He then took a professorship at Hamamatsu University School of Medicine. In thrombosis studies, he found the SK potentiator that enhances plasminogen activation by streptokinase. Using simultaneous analyses of plasma fatty acids, he indicated

that plasma levels of trans-fatty acids of old men were far higher in the US than Japanese men. By using simultaneous LC/MS analyses of plasma levels of tryptophan metabolites, he recently found that plasma levels of serotonin, kynurenine, or 5-HIAA were higher in patients of mono- and bipolar depression, which is significantly different from observations reported before. In view of recent reports that plasma tryptophan metabolites are mainly produced by microbiota, he is now working on the relationships between microbiota and depression or autism.

Contents

*by Yasuhiko Minokoshi*

Amino Acids

*and Tetsuya Takao*

*by Shinya Goto*

*by Yasuhiro Nishikawa*

*by Kenji Yokoyama*

Outcomes in Pregnancy *by Motoi Sugimura*

with Coronary Heart Disease

*by Hisao Nishijo and Taketoshi Ono*

**Preface XI**

**Chapter 1 1**

**Chapter 2 23**

**Chapter 3 41**

**Chapter 4 57**

**Chapter 5 69**

**Chapter 6 123**

**Chapter 7 137**

**Chapter 8 155**

Significance of Trans Fatty Acids and Omega-3 Fatty Acids in Japanese Men

*by Shinji Koba, Tetsuya Takao, Fumiko Shimizu, Mutsumi Ogawa, Yuuya Yokota,* 

Glucose or Sucrose Intakes and Plasma Levels of Essential and Nonessential

Neural Control of Homeostatic Feeding and Food Selection

Neural Mechanisms of Feeding Behavior and Its Disorders

*by Akikazu Takada, Fumiko Shimizu, Yukie Ishii, Mutsumi Ogawa* 

Mechanism of Thrombus Formation in Regard to Diet

Effects and Issues of Diet Fat on Cardiovascular Metabolism

Etiology of Cancer Associated Thromboembolism (CAT), and Diet, Lifestyle and Medicine to Reduce Cancer and Venous Thromboembolism

Metabolic Syndrome and Pathogenesis of Obesity-Related Adverse

*Fumiyoshi Tsunoda, Ken Arai, Toshiro Shinke and Akikazu Takada*
