7. Conclusion

Nodding syndrome (NS) is a childhood neurological disorder that occurs in clusters in Eastern Africa and of uncertain nosology. However, studies have demonstrated biotinidase and acetyl carnitine deficiency, Vitamin B6 deficiency, high anion gap metabolic acidosis and Vitamin D deficiency. In addition, NS children experienced internal displacement, fed on IDP diets which were mainly foreign to their GI microbiome and other environmental exposures, exposure to wartime situations and infectious diseases at childhood. Rehabilitated of NS children using home grown food supplement (MAMA supplement plus other symptomatic remedies), their conditions improved tremendously and some have returned to school

although there is no clear evidence that they have been completely cured. Furthermore, there are no new cases of NS as reported by the Ugandan Ministry of Health (MOH) and World Health Organization (WHO) since 2012 when the IDP camps were disbanded and communities resettled in their own communities and feed on their own home grown foods. Although these findings are inconclusive at this stage, perhaps NS observed in this region may be akin to autism spectrum disorder (ASD).

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