**2.5 Alkalide reduction: synthesis and characterization of gold nanoparticles and gold-coated gadolinium nanocrystals**

As of late, air, moisture and acid stable gold-covered gadolinium (Gd@Au) nanoparticles were set up by alkalide decrease. The union brought about center shell nanocrystals with a tight size appropriation. The Gd center could make the nanocrystals brilliant sub-atomic MRI differentiate specialists and give various alternatives to treatment of tumors, including 157Gd neutron catch treatment, photon initiation treatment, synchrotron stereotactic radiotherapy, and 159Gd radionuclide treatment. The Au shell anticipates Gd center from oxidation renders them stable even at low pH, which conceivably averts filtering and bio-inconsistency. T1 and T2 relaxivities demonstrate that Gd@Au nanocrystals are an extremely encouraging potential T1 MRI differentiate specialist [11].
