**2.6 Synthesis of a carborane gadolinium – DTPA complex for boron neutron capture therapy**

Hydrolysis of the ethyl esters in 1 was done with LiOH in fluid methanol pursued by treatment with weakened hydrochloric corrosive (1N) to bear the cost of

**39**

**Figure 7.**

*An Efficient Route for Synthesis of Macrocyclic Gadolinium Complexes and Their Role…*

**2.7 Single-crystal-to-single-crystal anion exchange in a GadoliniumMOF:** 

(otherwise called metal-natural structures, MOFs) has happened to incredible enthusiasm for ongoing years at the field of multifunctional materials. In this article, we present an investigation of the impacts of size and charge in the anion trade procedure of a Gd based MOF, including atomic species like

has been described by IR, EDAX, and single precious stone diffraction, which have given unequivocal proof of the area of the anion atoms in the structure [13]

**Form Supplied in:** commercially available as an anhydrous, white to off-

*(Top) view of the three crystallographically independent Gd centers in 1–AuCl4: Gd1, Gd2 and Gd3. Gd1 has a coordinated water molecule (in addition to 7 bridging bipyNO ligands), Gd2 has a terminal bipyNO ligand (in addition to 7 bridging bipyNO ligands), and Gd3 is coordinated to 8 bipyNO ligands that serve as bridges between Gd centers. (Bottom) close view of the coordination environment of Gd1 and Gd2, highlighting the* 

*presence of a terminal bipyNO ligand (in green) and a coordinated water molecule (in pink).*

. **Solubility:** soluble in water, ethanol, THF, acetone, acetonitrile, and other polar

the relating pentaacid 2 in 68% yield. Treatment of the carborane containing DTPA subordinate 2 with gadolinium(III) chloride hexahydrate gave the ideal Gd – DTPA

The exemplification of useful atoms inside permeable coordination polymers

<sup>−</sup>. This post-manufactured modification

*DOI: http://dx.doi.org/10.5772/intechopen.91180*

**incorporation of POMs and [AuCl]**

polyoxometalates '(POMs) and [AuCl4]

**2.8 Gadolinium(III) Trifluoromethanesulfonate**

**Alternate Name:** gadolinium(III) triflate. **Physical Data:** anhydrous, *d* = 7.07 g cm<sup>−</sup><sup>3</sup>

(**Figures 7** and **8**).

organic solvents.

white powder.

carborane complex 3 in quantitative yield (**Figure 6**) [12].

*An Efficient Route for Synthesis of Macrocyclic Gadolinium Complexes and Their Role… DOI: http://dx.doi.org/10.5772/intechopen.91180*

the relating pentaacid 2 in 68% yield. Treatment of the carborane containing DTPA subordinate 2 with gadolinium(III) chloride hexahydrate gave the ideal Gd – DTPA carborane complex 3 in quantitative yield (**Figure 6**) [12].
