**1. Introduction**

Developmental defects belong worldwide to leading causes of infant morbidity. Special interest deserve neural tube defects, that comprise anencephaly, spina bifida and encefalocele.

Spinal dysraphisms comprise a broad spectrum of congenital disorders resulting from impaired structural development of the craniospinal axis during brain and spinal cord growth and differentiation within 2nd and 6th week of gestation and proceed through a complex multistep process [1].

Spina bifida is a group of developmental disorders of neural tube. Neural tube in developing embryo forms future brain, spinal cord and their supporting structures. Under normal circumstances neural tube closes on 28th day after conception. In children with spina bifida neural tube does not develop or close properly causing dorsal defect of spine or spinal cord itself. Severity of symptoms and possible complications depends on location, size and type of defect.

Spina bifida is a complex disorder that requires multidisciplinary aproach in diagnostics, treatment and complications solving.
