**Acknowledgements**

*Interactive Multimedia - Multimedia Production and Digital Storytelling*

In the last few decades, there has been accelerating progress of technology and changes in the mode of human life. These states may give the appearance of approaching some essential singularity in the human history signalizing fears and concerns that the new superintelligence would continue to upgrade itself and annihilate humans considered ineffective and inefficient. Apart of science fiction, there is substantial ground that technological singularity started already with some applications of D-wave and processes of hidden Markov model (HMM) that run most of our daily and professional life [132]. HMM are useful in everyday life in many activities, such as speech recognition (e.g., Siri or Cortana), speech synthesis, speech tagging, machine translation, partial discharge, handwriting recognition, activity recognition, transportation forecasting. HMM is also useful in our professional life in activities, including single-molecule kinetic analysis, gene prediction, alignment of bio-sequences, deoxyribonucleic acid (DNA) motif discovery, time-series analysis, protein folding, chromatin state discovery, document separation in scanning solutions, sequence classification, metamorphic virus detection, solar irradiance variability, and computational finance. Although most individuals may suggest that the artificial superintelligence may be fully functional around 2050, there is no certainty that this may really happen. Multifractality and HMM-based integrated framework may represent two of the pathways to discover

In conclusion, the rapid advancement of information technology has allowed the gradual acceptance of DP in diagnostic routine and education. The use of digital pathology in clinical services may go back to the early steps using personal computers, such as Commodore 64, but is now well recognized in multi-site medical centers with more than one location as well as in geographically very diverse health sites. The use of quad-core processing, 5G technologies, and quantum biocomputing will change the image of colleges and universities in the 3rd decade of this

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it in the nearest future.

**14. Conclusions**

**Figure 1.**

*Evolutionary framework.*

This chapter is dedicated to the 73rd birthday of Professor Kim Solez, who is an American pathologist and co-founder of the Banff Classification, the first standardized international classification for renal allograft biopsies. In 2011, he pioneered a unique graduate-level medical course Technology and the Future of Medicine at the University of Alberta. I am honored to work with Professor Solez, whose contributions to digital pathology and artificial intelligence have been inspiring to me.
