Meet the editors

Prof. Eduardo Jacob-Lopes is currently an associate professor at the Department of Food Science and Technology, Federal University of Santa Maria. He has more than 18 years of teaching and research experience, and he is a technical and scientific consultant for several companies, agencies, and scientific journals. His 500 publications/communications include 8 books, 30 book chapters, 85 original research papers, and 360 research

communications in international and national conferences, and he has registered 15 patents. His research interests include biotechnology and bioengineering with emphasis on microalgal biotechnology.

Prof. Leila Queiroz Zepka is currently an associate professor at the Department of Food Science and Technology, Federal University of Santa Maria. She has more than 15 years of teaching and research experience, and she is a technical and scientific consultant for several companies, agencies, and scientific journals. Her 420 publications/communications include 8 books, 30 book chapters, 70 original research papers, and 300 research

communications in international and national conferences, and she has registered 10 patents. Her research interests include microalgal biotechnology with emphasis on biomolecules and natural pigments.

Contents

Sub-Saharan Africa

**Preface III**

**Chapter 1 1**

**Chapter 2 5**

**Chapter 3 21**

**Chapter 4 33** Hypotoxic Fluorescent Nanoparticles Delivery by Cell-Penetrating Peptides in

**Chapter 5 49**

**Chapter 6 61**

**Chapter 7 91**

**Chapter 8 105**

rhBMP-2-Coated Acellular Dermal Graft for Chronic Rotator Cuff Healing:

Structural Design, Fabrication and Evaluation of Resorbable Fiber-Based

Microbioreactors and Perfusion Bioreactors for Microbial and Mammalian

*by Selvan Ravindran, Pooja Singh, Sanjay Nene, Vinay Rale, Nutan Mhetras* 

*by Rosangela Rodrigues Dias, Leila Queiroz Zepka and Eduardo Jacob-Lopes*

Introductory Chapter: Biotechnology and Bioengineering

Developments and Perspectives in Bryophyte Biotechnology in

Multiple Organisms: From Prokaryotes to Mammalians Cells *by Betty Revon Liu, Yue-Wern Huang and Han-Jung Lee*

*by Martin W. King, Jiyang Chen, Monica Deshpande, Ting He, Harshini Ramakrishna, Yu Xie, Fan Zhang and Fan Zhao*

Steps and Tools for PCR-Based Technique Design *by Nelson Enrique Arenas and Luz Mary Salazar*

*by Kenneth Yongabi Anchang and Henrik Toft Simonsen*

*by Kwang-Il Lee, Ju-Woong Jang and Kwang-Won Lee*

Translational Tendon Repair Research

Integration of Membranes and Bioreactors *by Katalin Belafi-Bako and Peter Bakonyi*

Tissue Engineering Scaffolds

Cell Culture

*and Anuradha Vaidya*

## Contents



Preface

The book *Biotechnology and Bioengineering* shows how biotechnology and bioengineering can be used to solve the demands of modern society. In these eleven chapters, the book explores several important topics of biotechnology and bioengineering such as bioinstrumentation, biomaterials and nanotechnology, cell and tissue engineering and design, and application of bioreactors. The chapters are intended to help provide a deeper and wider understanding of the promises and challenges for biotechnology and bioengineering. This book is primarily dedicated to scientists, academicians, industrial representatives, and innovative technology representatives, and also to any nonspecialist reader willing to learn about the

> **Eduardo Jacob-Lopes and Leila Queiroz Zepka** Food Science and Technology Department,

> > Federal University of Santa Maria,

Santa Maria, RS, Brazil

dynamic field of biotechnology and bioengineering.
