**9.4 Sperm-oocyte fusion**

High concentration of docosahexaenoic acid (DHA) plays a considerable part in maintaining the fluidity of the membrane of spermatozoa. ROS enhances the fluidity of membrane and sperm-oocyte fusion rate, during the process of capacitation and acrosomal reaction. Throughout the entire capacitation process, ROS hinder the protein tyrosine phosphate activity and arrest the dephosphorylation and turnoff the phospholipase A2. PLA2 increases the fluidity of the membrane by cleaving the secondary fatty acid from the triglycerol backbone of membrane phospholipid [64, 65].
