Contents



Preface

This book is the result of contributions from many authors and researchers across the globe. Divided into four sections, this volume covers all the relevant clinical aspects of infertility. The first section elaborates on the recent understanding of infertility, which has developed as a result of newer imaging tools, serum hormone detections, and chemical analysis. The second section describes the recent developments in diagnosis and treatment of infertility. The third section covers the ethical and legal aspects of assisted reproductive technology (ART). The fourth section

The first chapter introduces the tools used to comprehend the physiology of reproduction. It elaborates the male factor and describes multiple environmental and epigenetic factors affecting spermatozoa and seminal plasma. The chapter also explains the etiologies and pathophysiology of diminished sperm quality. Since the etiology and pathogenesis is segregated and multifactorial, there are multitudes of resulting sperm defects. The second chapter describes these pathophysiological factors in detail. The third chapter explains the recent use of novel markers of semen analysis. The fourth chapter examines the biophysical and serum markers of oocyte reserve and quality. It also elaborates on the rational

The second section discusses the newer low molecular weight ligands of gonadotropins. It explains newer laboratory techniques of omics to help readers optimize ART results. It also presents the preparation and use of autologous platelet-rich plasma to improve endometrial receptivity in recurrent implantation failures. The chapter on recurrent implantation failure helps us to understand the intricacies of embryo– endometrial interactions. The chapter also provides meticulous detail regarding the practical procedure of in vitro maturation of oocytes. The in vitro culture of oocytes is likely to open new horizons of hope for cancer patients and patients who have repeated ovarian hyper stimulation syndromes. This technology also carries

The chapter on bioethics weighs the ethical and legal aspects of assisted reproduction

This book is an attempt to identify and standardize technology that is likely to improve ART outcomes. The basic scientific knowledge is valuable, pure, and self-correcting. Future studies are likely to provide new insights, developing these new concepts even further. We wish to express our gratitude to all the authors for their time, effort, and commitment in sharing their knowledge and skills. The authors have painstakingly prepared chapters and modified and proofread drafts despite all the laboratory work. Our sincere thanks to Ms. Mia Vulovic for communicating with all authors and singlehandedly coordinating this entire effort to ensure a final book of quality. We have to acknowledge the support of our publisher IntechOpen for their continuous guidance and support. Finally, we

in light of religious beliefs and provides insights into how far is far enough.

gives recent insights into contraception.

basis of drugs used for controlled hyper stimulation.

potential benefits of reducing cost and time.
