**3. Definitions of IVM in human**

The biological definition of oocyte IVM is to aspirate GV oocytes from antral follicles and culture them for in vitro maturation to a MII stage. Apart from routine IVF, the clinical definition of an IVM cycle should include an understanding that it involves the retrieval of oocytes from small and intermediate-sized follicles in an ovary before the largest follicle has surpassed 13 mm in mean diameter [21]. However, since modifications of the IVM technique are commonly employed, it is suggested, though, to designating the cycle when an oocyte trigger is given. When oocyte triggering is not performed, the cycle should be designated as IVM without triggering. When the addition of gonadotropin stimulation is given for few days in the early follicular phase, the cycle should be designated as IVM with short gonadotropin stimulation or modified natural cycle IVF with early triggering combined with IVM (if hCG or GnRh-agonist triggering was delivered) [21].
