**Author details**

Dorota Kopacz1,2\*, Łucja Niezgoda1 , Ewa Fudalej1 , Anna Nowak1 and Piotr Maciejewicz1,2

1 Medical University of Warsaw, Warsaw, Poland

2 Department of Ophthalmology, Infant Jesus Teaching Hospital, Warsaw, Poland

\*Address all correspondence to: dr.dk@wp.pl

© 2020 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

**11**

*Tear Film – Physiology and Disturbances in Various Diseases and Disorders*

[11] Daily PM. Structure and function of the tear film. Adv Exp Med Biol 1994,

[12] Bron A, Tiffany JM, Gouveia S, Yokoi N, Voon L; Functional aspects of the tear film lipid layer. Exp Eye Res

[13] Foulks GN; The correlation between the tear film lipid layer and dry eye disease. Surv Ophthalmol 2007,

[14] McCulley JP, Shine WE; The lipid layer of tears: dependent on Meibomian gland function. Exp Eye Res 2004,

[15] Davidson HJ, Kuonen VJ; The tear film and ocular mucins. Vet Ophthalmology 2004, 7(2):71-77

[16] Dartt DA; Regulation of tear secration. Adv Exp Med Biol 1994,

[17] Sullivan DA, Sullivan BD, Ulman MD, Rocha EM,

Krenzer KL, Cermak JM, Toda I, Doane MG, Evans JE, Wickham LA.: Androgen influence of the Meibomian gland. Invest Ophthalmol Vis Sci 2000,

[18] Conardy CD, Joos ZP, Patel BCK; Review: The lacrimal gland and its role in dry eye. J Ophthalmol 2016, 2016:7542929, doi: 10.1155/2016/ 7542929. Epub 2016 Mar 2.

[19] Iwata S; Chemical composition of the aqueous phase. Int Ophthalmol Clin Spring 1973;13(1):29-46.doi: 10.1097/00004397-197301310-00005.

[20] Kaura R, Tiffany JM; The role of mucous glykoproteins in the tear film. in: Holly FJ: The preocular tear film in health, disease and contact lens wear.

350:239-247

2004, 78:347-360

52(4):369-374

78:361-365

350:1-10

41(12): 3732-3742

*DOI: http://dx.doi.org/10.5772/intechopen.94142*

[1] Holland EJ, Mannis MJ, Lee WB: Ocular Surface Diseases, Elseviere Inc,

of the tear film: importance in homeostasis and dysfunction during disease. Exp Eye Res 2013,

[3] Stahl U, Willcox M, Stapleton F; Osmolality and tear film dynamics. Clin

[4] de Paiva CS, Pflugfelder SC; Tera clearance implications for ocular surface health. Ex Eye Res 2004,

[5] Mathers W; Evaporation from the ocular surface. Exp Eye Res 2004,

[6] Tiffany JM. The normal tear film. Dev Ophthalmol 2008, 41:1-20

[7] Willcox MDP, Argüeso P, Georgiev GA, Holopainen JM, Laurie GW, Millar TJ, Papas EB, Rolland JP, Schmidt TA, Stahl U, Suarez T, Subbaraman LN, Uçakhan OO, MDk, Jones L; TFOS DEWS II Tear Film Report. Ocul Surf. 2017 July ; 15(3): 366-403. doi:10.1016/j.

Exp Optom 2012, 95(1):3-11

December,117:1-3

78:395-397

78:389-394

jtos.2017.03.006.

12(4):252-266.

Soc 1997. 95:79-88

[8] Rolando M, Zierhut M; The ocular surface and tear film and their dysfunction in dry eye disease. Surv Ophthalmol 2001, 45(supl2):S203-210

[9] Yokoi, N., A.J. Bron, and G.A. Georgiev, The precorneal tear film as a fluid shell: the effect of blinking and saccades on tear film distribution and dynamics. Ocul Surf 2014,

[10] McCulley JP, Shine WA; A

compositional based model for the tear film lipid layer. Trans Am Ophthalmol

[2] Dartt DA, Willcox MDP; Complexity

2013

**References**

*Tear Film – Physiology and Disturbances in Various Diseases and Disorders DOI: http://dx.doi.org/10.5772/intechopen.94142*
