**3. General procedure for the synthesis of 1,4-disubstituted 1,2,3-triazole for compounds (111)**

Substituted organic halides (1.0 equiv), sodium azide (1.4 equiv) and substituted alkynes (1.104 equiv) were suspended in polyethylene glycol-400 (5 mL). To this copper iodide (10 mol%) was added and the re action mixture was stirred for 10–45 min at 25–35°C. After completion of the reaction (monitored by TLC), the product was extracted with EtOAc and the organic extract was dried. The crude product was recrystallized from ethanol to yield the desired product.
