**4.11 Synthesis of 1-(4-isocyanobenzyl)-4-p-tolyl-1H-1,2,3-triazole**

4-(Bromomethyl) benzonitrile 0.196 g (1.0 mmol), sodium azide 0.091 g (1.4 mmol) and 1-methyl-4-(prop-2-ynyloxy) benzene 0.160 g (1.1 mmol) were suspended in polyethylene glycol-400 (5 mL). To this reaction mixture in copper iodide (10 mol%) was added and the reaction mixture was stirred for 40 min at 35°C. After completion of the reaction (monitored by TLC), the product was extracted with EtOAc and the organic extract was dried. The crude product was recrystallized from ethanol to yield the desired product.

Yield: 7 8%, MF/FWt: C18H16N4O/304.13, MP: 144–146°C.

IR (cm<sup>−</sup><sup>1</sup> ): 3145, 2227, 1604, 1437, 1154, 857.

1 H NMR (300 MHz, CDCl3, δ ppm): 7.66–7.68 (d,2H), 7.34–7.36 (d,2H), 7.43–7.45 (d,2H), 7.84–7.86 (d,2H), 7.73 (s,1H, triazole), 5.61 (s,2H), 5.37 (s,2H), 2.56 (s,3H).
