**5. Conclusions**

In conclusion a safe and efficient method for the generation of 1,4-disubstituted 1,2,3-triazole in a complete regioselective manner has been developed. Synthesis of

1,2,3-triazole moiety is carried out for the first time by using PEG-400 as a green solvent. This methods are versatile, efficient and convenient. The methods required very short time as compared to reported methods for the synthesis of multicomponent 1,2,3-triazole and their heterocyclic compounds. Avoids the use of expensive volatile organic solvents and laborious work-up. Multicomponent method 1,2,3 triazole derivatives were synthesized. This method avoids isolation and handling of potentially unstable organic azide and provides triazole product in pure form 1,2,3-triazole moiety as a medicinal use.
