*2.3.2 Detection of drug molecules*

Zhou et al. designed and developed a convenient fluorescent sensor based on the molecularly imprinted polymers (MIPs)-functionalized GQDs for the detection of tetracycline (TC) with high sensitivity and high selectivity [25]. The GQDs were prepared by one-pot method, and the amino-functionalized GQDs and carboxylfunctionalized GQDs were fabricated, respectively. The GQD-MIPs were synthesized by sol-gel method. The GQD-MIPs exhibited strong fluorescence property, and the fluorescence was quenched upon addition of TC. The fluorescence quench efficiency showed a linear relationship with concentrations of TC between 1.0 and 104 μg/L. The detection limit was 1 μg/L.
