**Chapter 5**

*Beyond LEO - Human Health Issues for Deep Space Exploration*

dimorphic gene expression in human minor salivary glands. Oral Diseases.

2011;**17**:653-661

[94] Simmons DJ, Russell JE, Winter F, Baron R, Vignery A, Tran VT, et al. Bone growth in the rat mandible during space

flight. The Physiologist. 1980;

[95] Rosenberg GD, Campbell SC, Simmons DJ. The effects of spaceflight on the mineralization of rat incisor dentin. Proceedings of the Society for Experimental Biology and Medicine.

[96] Rosenberg GD, Simmons DJ. Electron microprobe analyses of Ca, S, Mg and P distribution in incisors of Spacelab-3 rats. The Physiologist.

Volozhin AI. [Comparative study of the effect of weightlessness and artificial gravity on the density, ash, calcium, and phosphorus content of calcified tissues]. Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina.

[98] Tang C, Niu Z, Zheng Y, Chen Y, Bao B. Meng Q. [Effects of hypergravity exposure after 30-days simulated weightlessness on chemokine CCL20 and its receptor CCR6 in lingual mucosa of rhesus macaque]. Zhonghua Yi Xue

Za Zhi. 2014;**94**:2525-2530

[99] Philippou A, Minozzo FC, Spinazzola JM, Smith LR, Lei H,

[100] Mukaibo T, Gao X, Yang NY, Oei MS, Nakamoto T, Melvin JE. Sexual dimorphisms in the transcriptomes of murine salivary glands. FEBS Open Bio. 2019;**9**:947-958. DOI: 10.1002/2211-5463.12625

[101] Michael D, Soi S, Cabera-Perez J, Weller M, Alexander S, Alevizos I, et al. Microarray analysis of sexually

Rassier DE, et al. Masticatory muscles of mouse do not undergo atrophy in space. The FASEB Journal. 2015;**29**:2769-2779

1985;**28**(6 Suppl):S189-S190

[97] Prokhonchukov AA, Komissarova NA, Zhizhina NA,

1980;**14**:23-26

**23**(Suppl 6):S87-S90

1984;**175**:429-437

**78**
