**6.9 Sheriff et al.**

Sheriff et al. proposed a reference framework for healthcare informatics and analytics by integrating IoT, complex event processing (CEP) and big data analytics [63]. This framework can serve as a reference in implementing a holistic healthcare informatics and analytics ecosystem. Integrating IoT, CEP and big data analytics technologies can solve specific problems. Specifically, CEP can support the realtime and near-real-time analytical processing of patient events from different sources by using big data and ubiquitous communication via IoT. In the future, Sheriff et al. are planning to use this framework as a foundation for developing a healthcare application system that can address the informatics and analytic needs of healthcare and other dependent industries. However, they did not test the performance of this framework [63]. This framework is illustrated in **Figure 16**.
