Meet the editor

Dr. Naofumi Shiomi studied recombinant yeast as a researcher at the Laboratory of Production Technology of Kanena Corporation for 15 years until 1998 and earned his PhD degree in Engineering from Kyoto University. He now works as a professor at the School of Human Sciences of Kobe College in Japan, where he teaches biotechnology and life science in his "Applied Life Science" laboratory. He has studied bioremediation and biomedical

science for 23 years at Kobe College and has published more than 50 papers and several books. His recent research has focused on the prevention of obesity and aging.

Contents

Technology *by Naofumi Shiomi*

*and Oscar A. Rojas-Rejón*

and Kefir Granules

A Stem Cell Perspective

Production

**Preface III**

**Chapter 1 1**

**Chapter 2 11**

**Chapter 3 29**

**Chapter 4 49**

**Chapter 5 69**

**Chapter 6 89**

**Chapter 7 105**

*Paola M. Alvarado Cóndor, Jimmy Núñez Pérez and Milton J. Cuaran Guerrero*

Introductory Chapter: Artificial Enzyme Produced by Directed Evolution

Fermentation: Metabolism, Kinetic Models, and Bioprocessing *by Carlos González-Figueredo, René Alejandro Flores-Estrella* 

Small-Scale Process for the Production of Kefiran through Culture Optimization by Use of Central Composite Design from Whey

Catalyst Development of Microbial Fuel Cells for Renewable-Energy

Integrated Biologics Manufacturing in Stirred-Suspension Bioreactor:

A Simple Way to Produce Gold Nanoshells for Cancer Therapy *by Rosa Isela Ruvalcaba Ontiveros, José Alberto Duarte Moller, Anel Rocío Carrasco Hernandez, Hilda Esperanza Esparza-Ponce, Erasmo Orrantia Borunda, Cynthia Deisy Gómez Esparza* 

Engineering of Surface Proteins in Extracellular Vesicles for

*by Stefan Vogt, Gerhard Stadlmayr, Johannes Grillari, Florian Rüker* 

*by José Manuel Pais-Chanfrau, Lorena D. Carrera Acosta,* 

*by Masayuki Azuma and Yoshihiro Ojima*

*by Suman C. Nath and Derrick E. Rancourt*

*and Juan Manuel Olivares Ramírez*

Tissue-Specific Targeting

*and Gordana Wozniak-Knopp*
